NMR chemical shielding and spin-spin coupling constants of liquid NHȝ: a systematic investigation using the sequential QM/MM method

The NMR spin coupling parameters, ¹J(N,H) and ²J(H,H), and the chemical shielding, σ(15N), of liquid ammonia are studied from a combined and sequential QM/MM methodology. Monte Carlo simulations are performed to generate statistically uncorrelated configurations that are submitted to density functio...

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Autores: Gester, Rodrigo M., Georg, Herbert C., Canuto, Sylvio, Caputo, Maria Cristina, Provasi, Patricio Federico
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2009
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/24732
Acesso em linha:http://hdl.handle.net/11336/24732
Access Level:acceso abierto
Palavra-chave:Solvent Effect
Chemical Shielding
Spin Spin Coupling Constant
https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
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network_acronym_str AR
network_name_str Argentina
repository_id_str
dc.title.none.fl_str_mv NMR chemical shielding and spin-spin coupling constants of liquid NHȝ: a systematic investigation using the sequential QM/MM method
title NMR chemical shielding and spin-spin coupling constants of liquid NHȝ: a systematic investigation using the sequential QM/MM method
spellingShingle NMR chemical shielding and spin-spin coupling constants of liquid NHȝ: a systematic investigation using the sequential QM/MM method
Gester, Rodrigo M.
Solvent Effect
Chemical Shielding
Spin Spin Coupling Constant
https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
title_short NMR chemical shielding and spin-spin coupling constants of liquid NHȝ: a systematic investigation using the sequential QM/MM method
title_full NMR chemical shielding and spin-spin coupling constants of liquid NHȝ: a systematic investigation using the sequential QM/MM method
title_fullStr NMR chemical shielding and spin-spin coupling constants of liquid NHȝ: a systematic investigation using the sequential QM/MM method
title_full_unstemmed NMR chemical shielding and spin-spin coupling constants of liquid NHȝ: a systematic investigation using the sequential QM/MM method
title_sort NMR chemical shielding and spin-spin coupling constants of liquid NHȝ: a systematic investigation using the sequential QM/MM method
dc.creator.none.fl_str_mv Gester, Rodrigo M.
Georg, Herbert C.
Canuto, Sylvio
Caputo, Maria Cristina
Provasi, Patricio Federico
author Gester, Rodrigo M.
author_facet Gester, Rodrigo M.
Georg, Herbert C.
Canuto, Sylvio
Caputo, Maria Cristina
Provasi, Patricio Federico
author_role author
author2 Georg, Herbert C.
Canuto, Sylvio
Caputo, Maria Cristina
Provasi, Patricio Federico
author2_role author
author
author
author
dc.subject.none.fl_str_mv Solvent Effect
Chemical Shielding
Spin Spin Coupling Constant
https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
topic Solvent Effect
Chemical Shielding
Spin Spin Coupling Constant
https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
description The NMR spin coupling parameters, ¹J(N,H) and ²J(H,H), and the chemical shielding, σ(15N), of liquid ammonia are studied from a combined and sequential QM/MM methodology. Monte Carlo simulations are performed to generate statistically uncorrelated configurations that are submitted to density functional theory calculations. Two different Lennard−Jones potentials are used in the liquid simulations. Electronic polarization is included in these two potentials via an iterative procedure with and without geometry relaxation, and the influence on the calculated properties are analyzed. B3LYP/aug-cc-pVTZ-J calculations were used to compute the ¹J(N,H) constants in the interval of −67.8 to −63.9 Hz, depending on the theoretical model used. These can be compared with the experimental results of −61.6 Hz. For the ²J(H,H) coupling the theoretical results vary between −10.6 to −13.01 Hz. The indirect experimental result derived from partially deuterated liquid is −11.1 Hz. Inclusion of explicit hydrogen bonded molecules gives a small but important contribution. The vapor-to-liquid shifts are also considered. This shift is calculated to be negligible for ¹J(N,H) in agreement with experiment. This is rationalized as a cancellation of the geometry relaxation and pure solvent effects. For the chemical shielding, σ(15N) calculations at the B3LYP/aug-pcS-3 show that the vapor-to-liquid chemical shift requires the explicit use of solvent molecules. Considering only one ammonia molecule in an electrostatic embedding gives a wrong sign for the chemical shift that is corrected only with the use of explicit additional molecules. The best result calculated for the vapor to liquid chemical shift Δσ(15N) is −25.2 ppm, in good agreement with the experimental value of −22.6 ppm.
publishDate 2009
dc.date.none.fl_str_mv 2009-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/24732
Gester, Rodrigo M.; Georg, Herbert C.; Canuto, Sylvio; Caputo, Maria Cristina; Provasi, Patricio Federico; NMR chemical shielding and spin-spin coupling constants of liquid NHȝ: a systematic investigation using the sequential QM/MM method; American Chemical Society; Journal of Physical Chemistry A; 113; 52; 9-2009; 14936-14942
1089-5639
1520-5215
CONICET Digital
CONICET
url http://hdl.handle.net/11336/24732
identifier_str_mv Gester, Rodrigo M.; Georg, Herbert C.; Canuto, Sylvio; Caputo, Maria Cristina; Provasi, Patricio Federico; NMR chemical shielding and spin-spin coupling constants of liquid NHȝ: a systematic investigation using the sequential QM/MM method; American Chemical Society; Journal of Physical Chemistry A; 113; 52; 9-2009; 14936-14942
1089-5639
1520-5215
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://pubs.acs.org/doi/abs/10.1021/jp9050484
info:eu-repo/semantics/altIdentifier/doi/10.1021/jp9050484
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1799196168902672384
spelling NMR chemical shielding and spin-spin coupling constants of liquid NHȝ: a systematic investigation using the sequential QM/MM methodGester, Rodrigo M.Georg, Herbert C.Canuto, SylvioCaputo, Maria CristinaProvasi, Patricio FedericoSolvent EffectChemical ShieldingSpin Spin Coupling Constanthttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1The NMR spin coupling parameters, ¹J(N,H) and ²J(H,H), and the chemical shielding, σ(15N), of liquid ammonia are studied from a combined and sequential QM/MM methodology. Monte Carlo simulations are performed to generate statistically uncorrelated configurations that are submitted to density functional theory calculations. Two different Lennard−Jones potentials are used in the liquid simulations. Electronic polarization is included in these two potentials via an iterative procedure with and without geometry relaxation, and the influence on the calculated properties are analyzed. B3LYP/aug-cc-pVTZ-J calculations were used to compute the ¹J(N,H) constants in the interval of −67.8 to −63.9 Hz, depending on the theoretical model used. These can be compared with the experimental results of −61.6 Hz. For the ²J(H,H) coupling the theoretical results vary between −10.6 to −13.01 Hz. The indirect experimental result derived from partially deuterated liquid is −11.1 Hz. Inclusion of explicit hydrogen bonded molecules gives a small but important contribution. The vapor-to-liquid shifts are also considered. This shift is calculated to be negligible for ¹J(N,H) in agreement with experiment. This is rationalized as a cancellation of the geometry relaxation and pure solvent effects. For the chemical shielding, σ(15N) calculations at the B3LYP/aug-pcS-3 show that the vapor-to-liquid chemical shift requires the explicit use of solvent molecules. Considering only one ammonia molecule in an electrostatic embedding gives a wrong sign for the chemical shift that is corrected only with the use of explicit additional molecules. The best result calculated for the vapor to liquid chemical shift Δσ(15N) is −25.2 ppm, in good agreement with the experimental value of −22.6 ppm.Fil: Gester, Rodrigo M.. Universidade de Sao Paulo; BrasilFil: Georg, Herbert C.. Universidade Federal de Goiás; Brasil. Universidade de Sao Paulo; BrasilFil: Canuto, Sylvio. Universidade de Sao Paulo; BrasilFil: Caputo, Maria Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; ArgentinaFil: Provasi, Patricio Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Modelado e Innovación Tecnológica. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas Naturales y Agrimensura. Instituto de Modelado e Innovación Tecnológica; ArgentinaAmerican Chemical Society2009-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/24732Gester, Rodrigo M.; Georg, Herbert C.; Canuto, Sylvio; Caputo, Maria Cristina; Provasi, Patricio Federico; NMR chemical shielding and spin-spin coupling constants of liquid NHȝ: a systematic investigation using the sequential QM/MM method; American Chemical Society; Journal of Physical Chemistry A; 113; 52; 9-2009; 14936-149421089-56391520-5215CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://pubs.acs.org/doi/abs/10.1021/jp9050484info:eu-repo/semantics/altIdentifier/doi/10.1021/jp9050484info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T14:17:19Zoai:ri.conicet.gov.ar:11336/24732instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 14:17:19.29CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
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