The hypophysis and secretion of insulin

The action of the hypophysis on the pancreas has been demonstrated by a number of direct and indirect proofs. The latter, first reported from this Institute, are as follows: (a) Complete kypophysectomy or anterior (distal) lobe removal produces: (1) Marked sensitivity to the hypoglycemic and toxic a...

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Detalles Bibliográficos
Autores: Houssay, Bernardo Alberto, Foglia, Virgilio G., Smyth, F. S., Rietti, Ciro T., Houssay, Alberto B.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1942
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/125031
Acceso en línea:http://hdl.handle.net/11336/125031
Access Level:acceso abierto
Palabra clave:HOUSSAY, BERNARDO ALBERTO
EL INVESTIGADOR
HOUSSAY EL INVESTIGADOR
PUBLICACIONES
DIABETES
PANCREATIC SECRETION
HYPOPHYSECTOMY
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
https://purl.org/becyt/ford/6.3
https://purl.org/becyt/ford/6
Descripción
Sumario:The action of the hypophysis on the pancreas has been demonstrated by a number of direct and indirect proofs. The latter, first reported from this Institute, are as follows: (a) Complete kypophysectomy or anterior (distal) lobe removal produces: (1) Marked sensitivity to the hypoglycemic and toxic action of insulin and other hypoglycemie agents such as phloridzin, fasting, etc. (2) Reduction of intensity of pancreatic and phloridzin diabetes. (3) A rapid fall in blood sugar and tissue glycogen during fasting; of non-pancreatic origin since it occurs after pancreatectomy. The hypoglycemic symptoms can be relieved by prompt administration of glucose, or prevented by a carbohydrate or protein, but not fat diet.