Diabetogenic action of different preparations of growth hormone

The diabetogenic action of the anterior pituitary growth hormone in dogs and cats which had been subjected to subtotal pancreatectomy was observed by Houssay and Anderson (1949 a and b). The dogs received growth hormone in dosages of 50 mg/kg/day and the cats, 25 mg/kg/day. The purpose of that study...

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Detalles Bibliográficos
Autores: Houssay, Bernardo A., Rodríguez, Ricardo Rosendo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1953
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/156702
Acceso en línea:http://hdl.handle.net/11336/156702
Access Level:acceso abierto
Palabra clave:HOUSSAY, BERNARDO ALBERTO
EL INVESTIGADOR
HOUSSAY EL INVESTIGADOR
PUBLICACIONES CIENTIFICAS
PUBLICACIONES
DIABETES
PITUITARY GLAND
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
Descripción
Sumario:The diabetogenic action of the anterior pituitary growth hormone in dogs and cats which had been subjected to subtotal pancreatectomy was observed by Houssay and Anderson (1949 a and b). The dogs received growth hormone in dosages of 50 mg/kg/day and the cats, 25 mg/kg/day. The purpose of that study was to find out the diabetogenic action, if any, of somatotrophin, adrenocorticotrophin and prolactin. The minimal effective doses were not investigated. In the present study, experiments were carried out a) to determine the minimal diabetogenic dose in subtotally depancreatized dogs, and b) to compare the diabetogenic action of three growth hormone preparations.