Heck, Sonogashira, and Hiyama Reactions Catalyzed by Palladium Nanoparticles Stabilized by Tris-Imidazolium Salt
Palladium nanoparticles, prepared by the hydrogenation of Pd(dba)2 in the presence of a tris-imidazolium iodide as stabilizer, act as an efficient catalyst for Heck and copper-free Sonogashira reactions with a range of aryl iodides and bromides at 0.2 mol-% Pd loading. Moreover, we describe a conven...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2014 |
| País: | Argentina |
| Institución: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/30493 |
| Acceso en línea: | http://hdl.handle.net/11336/30493 |
| Access Level: | acceso abierto |
| Palabra clave: | Heck Reactions Sonogashira Reactions Hiyama Reactions Palladium Nanoparticles https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
| Sumario: | Palladium nanoparticles, prepared by the hydrogenation of Pd(dba)2 in the presence of a tris-imidazolium iodide as stabilizer, act as an efficient catalyst for Heck and copper-free Sonogashira reactions with a range of aryl iodides and bromides at 0.2 mol-% Pd loading. Moreover, we describe a convenient protocol for the fluoride-free Hiyama coupling of vinylsilanes with aryl iodides that involves the use of sodium hydroxide as promoter in a methanol/water mixture. Under the developed conditions, one-pot, double Heck and Hiyama–Heck reactions are successfully achieved. |
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