Very efficient and broad-in-scope palladium-catalyzed Hiyama cross-coupling: The role of water and copper(I) salts

A very high-yielding Pd-catalyzed cross-coupling between aryl halides and aryl(trialkoxy)silanes is achieved in the presence of Cu(i) and a measured amount of water. This novel methodology is useful for the generation of a wide range of biaryls, particularly non-para substituted derivatives, which a...

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Detalles Bibliográficos
Autores: Traficante, Carla Inés, Mata, Ernesto Gabino, Delpiccolo, Carina Maria Lujan
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/127128
Acceso en línea:http://hdl.handle.net/11336/127128
Access Level:acceso abierto
Palabra clave:Cross-coupling reactions
Biaryl derivatives
Hiyama coupling
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descripción
Sumario:A very high-yielding Pd-catalyzed cross-coupling between aryl halides and aryl(trialkoxy)silanes is achieved in the presence of Cu(i) and a measured amount of water. This novel methodology is useful for the generation of a wide range of biaryls, particularly non-para substituted derivatives, which are usually less reported.