Efficient routes to racemic and enantiomerically pure (S)-BINOL diesters

A systematic study for esterification procedures to the synthesis of BINOL diesters is described. Reaction conditions with TFAA and 85% H3PO4 were selected as the best procedure to prepare enantiomerically pure (S)-BINOL diesters VIII to XI with almost quantitative yields and very low reaction times...

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Detalles Bibliográficos
Autores: Costantino, Andrea Rosana, Ocampo, Romina Andrea, Montiel Schneider, María Gabriela, Fernandez, Gustavo Adrian, Koll, Liliana Cristina, Mandolesi, Sandra Delia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/5307
Acceso en línea:http://hdl.handle.net/11336/5307
Access Level:acceso abierto
Palabra clave:DIOLS
ESTERIFICATION
PHASE-TRANSFER CATALYSIS
DIESTERS
BINOL
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descripción
Sumario:A systematic study for esterification procedures to the synthesis of BINOL diesters is described. Reaction conditions with TFAA and 85% H3PO4 were selected as the best procedure to prepare enantiomerically pure (S)-BINOL diesters VIII to XI with almost quantitative yields and very low reaction times.