Efficient Routes to Racemic and Enantiomerically Pure (S)-BINOL Diesters

A systematic study for esterification procedures to the synthesis of BINOL diesters is described. Reaction conditions with TFAA and 85% H3PO4 were selected as the best procedure to prepare enantiomerically pure (S)-BINOL diesters VIII to XI with almost quantitative yields and very low reaction times...

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Bibliographic Details
Authors: Costantino, Andrea Rosana, Ocampo, Romina Andrea, Montiel Schneider, María Gabriela, Fernández, Gustavo Alejandro, Koll, Liliana Cristina, Mandolesi, Sandra Delia
Format: article
Status:Published version
Publication Date:2013
Country:Argentina
Institution:Consejo Nacional de Investigaciones Científicas y Técnicas
Repository:CONICET Digital (CONICET)
Language:English
OAI Identifier:oai:ri.conicet.gov.ar:11336/101840
Online Access:http://hdl.handle.net/11336/101840
Access Level:Open access
Keyword:DIOLS
ESTERIFICATION
PHASE-TRANSFER CATALYSIS
DIESTERS
BINOL
C2 SYMETRY
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Description
Summary:A systematic study for esterification procedures to the synthesis of BINOL diesters is described. Reaction conditions with TFAA and 85% H3PO4 were selected as the best procedure to prepare enantiomerically pure (S)-BINOL diesters VIII to XI with almost quantitative yields and very low reaction times.

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