Nucleophilic non-metal assited trifluoromethylation and perfluoroalkylation reactions of organic substrates

Nucleophilic trifluoromethylation and perfluoroalkylation reactions have been the outstanding approach during the last few decades to effect fluoroalkyl group addition or substitution reactions. In most instances, perfluoroalkyl-metal species participate at the beginning of the reactions. In this ac...

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Detalles Bibliográficos
Autores: Barata Vallejo, Sebastian, Torviso, Maria del Rosario, Lantaño, Beatriz, Bonesi, Sergio Mauricio, Postigo, Jose Alberto
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/30212
Acceso en línea:http://hdl.handle.net/11336/30212
Access Level:acceso abierto
Palabra clave:Nucleophilic trifluoromethylation
Fluoroform
Trimethylsilyltrifluoromethane
Fluorinated sulfones
Fluorinated sulfoxides
Fluorinated sulfides
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descripción
Sumario:Nucleophilic trifluoromethylation and perfluoroalkylation reactions have been the outstanding approach during the last few decades to effect fluoroalkyl group addition or substitution reactions. In most instances, perfluoroalkyl-metal species participate at the beginning of the reactions. In this account, however, the latest nucleophilic non-metal assisted or uncatalyzed trifluoromethylation and perfluoroalkylation reactions of substrates bearing biological relevance will be discussed.