Spread of clonally related escherichia coli strains harboring an IncA/C1Plasmid encoding IMP-8 and its recruitment into an unrelated MCR-1-containing isolate
Ten IMP-8-producing Escherichia coli isolates were recovered from surveillance cultures of a neonatal intensive care unit; eight of the isolates were clonally related. A 168.2-kb blaIMP-8 plasmid was fully sequenced, and it corresponded to the recently described IncA/C1-ST13 plasmid. This plasmid wa...
| Authors: | , , , , , , , |
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| Format: | article |
| Status: | Published version |
| Publication Date: | 2018 |
| Country: | Argentina |
| Institution: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repository: | CONICET Digital (CONICET) |
| Language: | English |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/99334 |
| Online Access: | http://hdl.handle.net/11336/99334 |
| Access Level: | Open access |
| Keyword: | ESCHERICHIA COLI IMP-8 METALLO-BETA-LACTAMASE INCA/C1 PLASMID INCI2 PLASMID MCR-1 https://purl.org/becyt/ford/3.3 https://purl.org/becyt/ford/3 |
| Summary: | Ten IMP-8-producing Escherichia coli isolates were recovered from surveillance cultures of a neonatal intensive care unit; eight of the isolates were clonally related. A 168.2-kb blaIMP-8 plasmid was fully sequenced, and it corresponded to the recently described IncA/C1-ST13 plasmid. This plasmid was detected in all isolates, even in those that were not clonally related. One unrelated isolate was also resistant to colistin and positive for mcr-1. This marker was located in a 62.7-kb IncI2 plasmid, which was also fully sequenced. |
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