Immune-neuroendocrine and metabolic disorders in human and experimental T. cruzi infection: New clues for understanding Chagas disease pathology

Studies in mice undergoing acute Trypanosoma cruzi infection and patients with Chagas disease, led to identify several immune-neuroendocrine disturbances and metabolic disorders. Here, we review relevant findings concerning such abnormalities and discuss their possible influence on disease physiopat...

Full description

Bibliographic Details
Authors: González, Florencia Belén, Villar, Silvina Raquel, Pacini, María Florencia, Bottasso, Oscar Adelmo, Perez, Ana Rosa
Format: article
Status:Published version
Publication Date:2020
Country:Argentina
Institution:Consejo Nacional de Investigaciones Científicas y Técnicas
Repository:CONICET Digital (CONICET)
Language:English
OAI Identifier:oai:ri.conicet.gov.ar:11336/148728
Online Access:http://hdl.handle.net/11336/148728
Access Level:Open access
Keyword:ADIPOSE TISSUE
CHAGAS DISEASE
GLUCOCORTICOIDS
HYPOTHALAMUS-PITUITARY-ADRENAL AXIS
IL-1 BETA
PPAR-Γ
https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
Description
Summary:Studies in mice undergoing acute Trypanosoma cruzi infection and patients with Chagas disease, led to identify several immune-neuroendocrine disturbances and metabolic disorders. Here, we review relevant findings concerning such abnormalities and discuss their possible influence on disease physiopathology.

Similar Items