Immune-neuroendocrine and metabolic disorders in human and experimental T. cruzi infection: New clues for understanding Chagas disease pathology

Studies in mice undergoing acute Trypanosoma cruzi infection and patients with Chagas disease, led to identify several immune-neuroendocrine disturbances and metabolic disorders. Here, we review relevant findings concerning such abnormalities and discuss their possible influence on disease physiopat...

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Detalhes bibliográficos
Autores: González, Florencia Belén, Villar, Silvina Raquel, Pacini, María Florencia, Bottasso, Oscar Adelmo, Perez, Ana Rosa
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/148728
Acesso em linha:http://hdl.handle.net/11336/148728
Access Level:acceso abierto
Palavra-chave:ADIPOSE TISSUE
CHAGAS DISEASE
GLUCOCORTICOIDS
HYPOTHALAMUS-PITUITARY-ADRENAL AXIS
IL-1 BETA
PPAR-Γ
https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
Descrição
Resumo:Studies in mice undergoing acute Trypanosoma cruzi infection and patients with Chagas disease, led to identify several immune-neuroendocrine disturbances and metabolic disorders. Here, we review relevant findings concerning such abnormalities and discuss their possible influence on disease physiopathology.

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