Biocompatibility and photo-induced antibacterial activity of lignin-stabilized noble metal nanoparticles

One-pot thermal and photochemical syntheses of lignin-doped silver and gold nanoparticles were developed and their antimicrobial properties were studied against Escherichia coli and Staphylococcus aureus. The nature of the lignin as well as the metal are directly involved in the antimicrobial activi...

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Detalles Bibliográficos
Autores: Rocca, Diamela María, Vanegas, Julie P., Fournier, Kelsey, Becerra, María Cecilia, Scaiano, Juan Cesar, Lanterna, Anabel Estela
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/87910
Acceso en línea:http://hdl.handle.net/11336/87910
Access Level:acceso abierto
Palabra clave:BIOCOMPATIBILITY
NOBLE NANOPARTICLES
LIGNIN
ANTIBACTERIAL
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descripción
Sumario:One-pot thermal and photochemical syntheses of lignin-doped silver and gold nanoparticles were developed and their antimicrobial properties were studied against Escherichia coli and Staphylococcus aureus. The nature of the lignin as well as the metal are directly involved in the antimicrobial activity observed in these nanocomposites. Whereas one of the nanocomposites is innocuous under dark conditions and shows photoinduced activity only against Staphylococcus aureus, the rest of the lignin-coated silver nanoparticles studied show antimicrobial activity under dark and light conditions for both bacteria strains. Additionally, only photoinduced activity is observed for lignin-coated gold nanoparticles. Importantly, the particles are non-cytotoxic towards human cells at the bactericidal concentrations. Preliminary assays show these silver nanoparticles as potential antimicrobial agents towards S. aureus biofilm eradication.