Rapid and efficient synthesis of five- to eight-membered cyclic aminals under ultrasound irradiation

A simple, efficient, and green procedure has been developed for the synthesis of cyclic aminals from alkylenediamines and aqueous formaldehyde under ultrasound irradiation. Applying this methodology a series of five-to eight-membered 1,3-dibenzyl substituted aminals were synthesized in excellent yie...

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Detalles Bibliográficos
Autores: Ramírez, María Amelia, Ortiz, Gisela, Levin, Gustavo Javier, Mac Cormack, Walter Patricio, Blanco, María de Las Mercedes, Perillo, Isabel Amalia, Salerno, Alejandra
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/30604
Acceso en línea:http://hdl.handle.net/11336/30604
Access Level:acceso abierto
Palabra clave:Cyclic Aminals
Alkylenediamines
Ultrasonic Assisted Synthesis
Green Chemistry
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descripción
Sumario:A simple, efficient, and green procedure has been developed for the synthesis of cyclic aminals from alkylenediamines and aqueous formaldehyde under ultrasound irradiation. Applying this methodology a series of five-to eight-membered 1,3-dibenzyl substituted aminals were synthesized in excellent yields after short reaction times. Results were compared to thermal conventional method. All novel compounds were identified and characterized by 1H and 13C NMR spectra.