A fast fluorimetric flow injection method to determine ibuprofen

The native fluorescence of ibuprofen was enhanced when a host-guest complex of the analyte with b cyclodextrin (b-CD) was formed. So, based on this fact, a flow injection method to determine ibuprofen in different pharmaceutical preparations with fluorescence detection (lem 287 nm, lexc 223 nm) was...

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Detalles Bibliográficos
Autores: Lista, Adriana Guillermina, Palomeque, Miriam Edid, Fernández Band, Beatriz Susana
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2006
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/119419
Acceso en línea:http://hdl.handle.net/11336/119419
Access Level:acceso abierto
Palabra clave:IBUPROFEN
FIA
SPECTROFLUORIMETRIC
PHARMACEUTICAL PREPARATION
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
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network_acronym_str AR
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repository_id_str
spelling A fast fluorimetric flow injection method to determine ibuprofenLista, Adriana GuillerminaPalomeque, Miriam EdidFernández Band, Beatriz SusanaIBUPROFENFIASPECTROFLUORIMETRICPHARMACEUTICAL PREPARATIONhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1The native fluorescence of ibuprofen was enhanced when a host-guest complex of the analyte with b cyclodextrin (b-CD) was formed. So, based on this fact, a flow injection method to determine ibuprofen in different pharmaceutical preparations with fluorescence detection (lem 287 nm, lexc 223 nm) was developed. The calibration curve was linear over the range 6.00 – 60.0 mg L-1 of ibuprofen and the detection limit (LOD) for S/N=3 was 4.5 mg L-1. The relative standard deviation was 1.2% and the sample throughput 240 h-1. The method was validated by comparing the proposed and the official method to commercial preparation samples.A fluorescência natural da ibuprofeína foi melhorada quando foi formado um complexo convidado-hospedeiro com a beta-ciclodextrina (beta-CD). A partir disso, foi desenvolvido um método por injeção em fluxo para a determinação de ibuprofeína em diferentes preparações farmacêuticas, com detecção fluorescente (lem 287 nm, lex 233 nm). A curva de calibração foi linear no intervalo entre 6,00 a 60,0 mg L-1 de ibuprofeína, com limite de detecção (LOD para S/N=3) de 4,5 mg L-1. O desvio padrão relativo foi de 1,2% e a velocidade de determinação de 240 amostras por hora. O método foi validado pela comparação do método proposto, e do usado oficialmente, em amostras comerciais preparadas.Fil: Lista, Adriana Guillermina. Universidad Nacional del Sur. Departamento de Química. Química Analitica; ArgentinaFil: Palomeque, Miriam Edid. Universidad Nacional del Sur. Departamento de Química. Química Analitica; ArgentinaFil: Fernández Band, Beatriz Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; ArgentinaSociedade Brasileira de Química2006-12-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/119419Lista, Adriana Guillermina; Palomeque, Miriam Edid; Fernández Band, Beatriz Susana; A fast fluorimetric flow injection method to determine ibuprofen; Sociedade Brasileira de Química; Journal of the Brazilian Chemical Society; 17; 7; 10-12-2006; 1428-14310103-50531678-4790CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1590/S0103-50532006000700033info:eu-repo/semantics/altIdentifier/url/https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532006000700033&lng=en&nrm=iso&tlng=eninfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T14:05:35Zoai:ri.conicet.gov.ar:11336/119419instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 14:05:35.296CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv A fast fluorimetric flow injection method to determine ibuprofen
title A fast fluorimetric flow injection method to determine ibuprofen
spellingShingle A fast fluorimetric flow injection method to determine ibuprofen
Lista, Adriana Guillermina
IBUPROFEN
FIA
SPECTROFLUORIMETRIC
PHARMACEUTICAL PREPARATION
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
title_short A fast fluorimetric flow injection method to determine ibuprofen
title_full A fast fluorimetric flow injection method to determine ibuprofen
title_fullStr A fast fluorimetric flow injection method to determine ibuprofen
title_full_unstemmed A fast fluorimetric flow injection method to determine ibuprofen
title_sort A fast fluorimetric flow injection method to determine ibuprofen
dc.creator.none.fl_str_mv Lista, Adriana Guillermina
Palomeque, Miriam Edid
Fernández Band, Beatriz Susana
author Lista, Adriana Guillermina
author_facet Lista, Adriana Guillermina
Palomeque, Miriam Edid
Fernández Band, Beatriz Susana
author_role author
author2 Palomeque, Miriam Edid
Fernández Band, Beatriz Susana
author2_role author
author
dc.subject.none.fl_str_mv IBUPROFEN
FIA
SPECTROFLUORIMETRIC
PHARMACEUTICAL PREPARATION
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
topic IBUPROFEN
FIA
SPECTROFLUORIMETRIC
PHARMACEUTICAL PREPARATION
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
description The native fluorescence of ibuprofen was enhanced when a host-guest complex of the analyte with b cyclodextrin (b-CD) was formed. So, based on this fact, a flow injection method to determine ibuprofen in different pharmaceutical preparations with fluorescence detection (lem 287 nm, lexc 223 nm) was developed. The calibration curve was linear over the range 6.00 – 60.0 mg L-1 of ibuprofen and the detection limit (LOD) for S/N=3 was 4.5 mg L-1. The relative standard deviation was 1.2% and the sample throughput 240 h-1. The method was validated by comparing the proposed and the official method to commercial preparation samples.
publishDate 2006
dc.date.none.fl_str_mv 2006-12-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/119419
Lista, Adriana Guillermina; Palomeque, Miriam Edid; Fernández Band, Beatriz Susana; A fast fluorimetric flow injection method to determine ibuprofen; Sociedade Brasileira de Química; Journal of the Brazilian Chemical Society; 17; 7; 10-12-2006; 1428-1431
0103-5053
1678-4790
CONICET Digital
CONICET
url http://hdl.handle.net/11336/119419
identifier_str_mv Lista, Adriana Guillermina; Palomeque, Miriam Edid; Fernández Band, Beatriz Susana; A fast fluorimetric flow injection method to determine ibuprofen; Sociedade Brasileira de Química; Journal of the Brazilian Chemical Society; 17; 7; 10-12-2006; 1428-1431
0103-5053
1678-4790
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1590/S0103-50532006000700033
info:eu-repo/semantics/altIdentifier/url/https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532006000700033&lng=en&nrm=iso&tlng=en
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 15,811543

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