Characterization of biodegradable polymers irradiated with swift heavy ions

In view of their application as biomaterials, there is an increasing interest in developing new methods to induce controlled cell adhesion onto polymeric materials. The critical step in all these methods involves the modification of polymer surfaces, to induce cell adhesion, without changing theirs...

ver descrição completa

Detalhes bibliográficos
Autores: Salguero, N. G., del Grosso, Mariela Fernanda, Duran, Hebe Alicia, Peruzzo, Pablo Jose, Amalvy, Javier, Arbeitman, Claudia Roxana, Garcia Bermudez, Gerardo Jose
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2012
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositório:CONICET Digital (CONICET)
Idioma:inglês
OAI Identifier:oai:ri.conicet.gov.ar:11336/196604
Acesso em linha:http://hdl.handle.net/11336/196604
Access Level:Acceso aberto
Palavra-chave:BIOCOMPATIBILITY
BIOPOLYMERS
IRRADIATED POLYMERS
SWIFT HEAVY IONS
https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
Descrição
Resumo:In view of their application as biomaterials, there is an increasing interest in developing new methods to induce controlled cell adhesion onto polymeric materials. The critical step in all these methods involves the modification of polymer surfaces, to induce cell adhesion, without changing theirs degradation and biocompatibility properties. In this work two biodegradable polymers, polyhydroxybutyrate (PHB) and poly-L-lactide acid (PLLA) were irradiated using carbon and sulfur beams with different energies and fluences. Pristine and irradiated samples were degradated by immersion in a phosphate buffer at pH 7.0 and then characterized. The analysis after irradiation and degradation showed a decrease in the contact angle values and changes in their crystallinity properties.