Characterization of biodegradable polymers irradiated with swift heavy ions

In view of their application as biomaterials, there is an increasing interest in developing new methods to induce controlled cell adhesion onto polymeric materials. The critical step in all these methods involves the modification of polymer surfaces, to induce cell adhesion, without changing theirs...

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Detalles Bibliográficos
Autores: Salguero, N. G., del Grosso, Mariela Fernanda, Duran, Hebe Alicia, Peruzzo, Pablo Jose, Amalvy, Javier, Arbeitman, Claudia Roxana, Garcia Bermudez, Gerardo Jose
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/196604
Acceso en línea:http://hdl.handle.net/11336/196604
Access Level:acceso abierto
Palabra clave:BIOCOMPATIBILITY
BIOPOLYMERS
IRRADIATED POLYMERS
SWIFT HEAVY IONS
https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
Descripción
Sumario:In view of their application as biomaterials, there is an increasing interest in developing new methods to induce controlled cell adhesion onto polymeric materials. The critical step in all these methods involves the modification of polymer surfaces, to induce cell adhesion, without changing theirs degradation and biocompatibility properties. In this work two biodegradable polymers, polyhydroxybutyrate (PHB) and poly-L-lactide acid (PLLA) were irradiated using carbon and sulfur beams with different energies and fluences. Pristine and irradiated samples were degradated by immersion in a phosphate buffer at pH 7.0 and then characterized. The analysis after irradiation and degradation showed a decrease in the contact angle values and changes in their crystallinity properties.