Effect of dilution rate on the release of pertussis toxin and lipopolysaccharide of Bordetella pertussis

The kinetics of Bordetella pertussis growth was studied in a glutamate-limited continuous culture. Growth kinetics corresponded to Monod's model. The saturation constant and maximum specific growth rate were estimated as well as the energetic parameters, theoretical yield of cells and maintenan...

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Detalles Bibliográficos
Autores: Rodríguez, María Eugenia, Hozbor, Daniela Flavia, Samo, Analia L., Ertola, Rodolfo J., Yantorno, Osvaldo Miguel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1994
País:Argentina
Institución:Universidad Nacional de La Plata
Repositorio:SEDICI (UNLP)
Idioma:inglés
OAI Identifier:oai:sedici.unlp.edu.ar:10915/146136
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/146136
Access Level:acceso abierto
Palabra clave:Biología
Bordetella pertussis
Kinetics
Descripción
Sumario:The kinetics of Bordetella pertussis growth was studied in a glutamate-limited continuous culture. Growth kinetics corresponded to Monod's model. The saturation constant and maximum specific growth rate were estimated as well as the energetic parameters, theoretical yield of cells and maintenance coefficient. Release of pertussis toxin (PT) and lipopolysaccharide (LPS) were growth-associated. In addition, they showed a linear relationship between them. Growth rate affected neither outer membrane proteins nor the cell-bound LPS pattern.