Histopathological case study of canine hemangiosarcoma with multiple organ metastases

We studied a 14-year-old male dog necropsied. Gross findings were hemorrhagic nodules in the spleen, liver, heart and abdominal and thoracic lymph nodes. Histologically, we homogeneously observed tumor cells often with prominent, bulging and mitotic nuclei that were pleomorphic and hyperchromatic, f...

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Bibliographic Details
Authors: Varela Cruces, María Belén, Larrañaga Sposito, Camila, Yamasaki, Kanji, Verdes García, José Manuel
Format: article
Status:Published version
Publication Date:2022
Country:Uruguay
Institution:Universidad de la República
Repository:COLIBRI
Language:English
OAI Identifier:oai:colibri.udelar.edu.uy:20.500.12008/48306
Online Access:https://hdl.handle.net/20.500.12008/48306
Access Level:Open access
Keyword:PERROS
PEQUEÑOS ANIMALES
PATOLOGIA
NEOPLASMAS
Description
Summary:We studied a 14-year-old male dog necropsied. Gross findings were hemorrhagic nodules in the spleen, liver, heart and abdominal and thoracic lymph nodes. Histologically, we homogeneously observed tumor cells often with prominent, bulging and mitotic nuclei that were pleomorphic and hyperchromatic, forming small blood vessels. Tumors in all organs were diagnosed as capillary hemangiosarcomas. No tumor cells were detected in the lungs. We presume that the primary tumor was present in the spleen, from where it metastasized multiple organs via lymphatic vessels.