Use of the Scottish and Newcastle Anti-Emetic Pretreatment (SNAP) scheme in recovery from massive overdose of acetaminophen poisoning with acute liver failure - Case report

 Acetaminophen is a drug widely used in the world and easily accessible due to its antipyretic, analgesics characteristics, among others (1); however, exposure to toxic doses causes organic damage and even death. We present the case of an 18-year-old female patient who ingested 40 grams of acetamino...

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Detalles Bibliográficos
Autores: Torres-Maure, Moisés, Tapia-Ibáñez, E. Ximena, Gamarra-Lázaro, Angello, Bellido-Caparó, Álvaro, García-Encinas, Carlos
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:Perú
Institución:Sociedad de Gastroenterología del Perú
Repositorio:Revista de Gastroenterología del Perú
Idioma:español
OAI Identifier:oai:ojs.revistagastroperu.com:article/1400
Acceso en línea:https://revistagastroperu.com/index.php/rgp/article/view/1400
Access Level:acceso abierto
Palabra clave:Acetaminofén
Intoxicación
N-acetilcisteína
Hepatotoxicidad
SNAP
falla hepática aguda
paracetamol.
Descripción
Sumario: Acetaminophen is a drug widely used in the world and easily accessible due to its antipyretic, analgesics characteristics, among others (1); however, exposure to toxic doses causes organic damage and even death. We present the case of an 18-year-old female patient who ingested 40 grams of acetaminophen and developed severe liver dysfunction, being treated with N-acetylcysteine (NAC) antidotal therapy according to the simplified scheme: Scottish and Newcastle Anti-emetic Pretreatment Paracetamol Poisoning Study Regimen (SNAP), presenting improvement in the clinical course and decrease in liver profiles, coagulation disorder, INR and resolution of the condition.