Determination of the standardized uptake value (SUV) of 18F-FDG in PET/CT in the simulation of lesions less than or equal to 10 millimeters in air and lung mannequin
Positron emission tomography (PET) images contribute to the metabolic evaluation of lesions at all stages using the radiopharmaceutical 18F-FDG (Fluorine-18-fluorodeoxyglucose); oncology is its main indication. The most used parameter is the standardized uptake value (SUV). Studies suggest further r...
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2025 |
| País: | Perú |
| Institución: | Universidad Peruana Cayetano Heredia |
| Repositorio: | Revistas - Universidad Peruana Cayetano Heredia |
| Idioma: | español |
| OAI Identifier: | oai:revistas.upch.edu.pe:article/7044 |
| Acceso en línea: | https://revistas.upch.edu.pe/index.php/RMH/article/view/7044 |
| Access Level: | acceso abierto |
| Palabra clave: | Tomografía de emisión de positrones fluorodesoxiglucosa F18 lesión pulmonar Positron-Emission Tomography Fluorodeoxyglucose F18 lung lesion |
| Sumario: | Positron emission tomography (PET) images contribute to the metabolic evaluation of lesions at all stages using the radiopharmaceutical 18F-FDG (Fluorine-18-fluorodeoxyglucose); oncology is its main indication. The most used parameter is the standardized uptake value (SUV). Studies suggest further research into the metabolic quantification of lesions ≤ 10 mm in PET. Objective: To determine the accuracy of SUV in the simulation of lesions ≤ 10 mm in air and lung mannequin with point radioactive sources of 18F-FDG. Methods: Experimental study based on 36 simulations in air and 36 simulations in a lung mannequin. Measures of central tendency were described, and the medians of SUVPET and SUV theoretical in air and lung mannequin were compared using the non-parametric Wilcoxon-Mann-Whitney test. Results: SUV accuracy in simulations of lesions ≤10 mm showed systematic overestimation, greather in air than in the lung mannequin, exceeding the 5% uncertainty recommended by the International Atomic Energy Agency (IAEA). Conclusions: The accuracy percentage of SUVPETmax, SUVPETmed and SUVPETmin values presented a value greather than 5%; the estimates showed significant deviation for this size range, making SUV quantification difficult for lesions smaller than 10mm. |
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