Subcutaneous versus intravenous administration of Trastuzumab: a minimization cost analysis with real world data from a reference cancer centre in Peru

Breast cancer (BC) is a global concern, with Peru experiencing a high incidence and mortality. Trastuzumab, a crucial treatment for human epidermal growth factor receptor 2-positive BC, is administered intravenously or subcutaneously (SC). This study evaluates the costs associated with both methods...

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Detalles Bibliográficos
Autores: Otoya, I, Valdiviezo, N, Roque, K, Morante, Z, Vidaurre, T, Neciosup, SP, Calderón, MJ, Gomez, HL
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:Perú
Institución:Instituto Nacional de Enfermedades Neoplásicas
Repositorio:INEN-Institucional
Idioma:inglés
OAI Identifier:oai:repositorio.inen.sld.pe:20.500.14703/400
Acceso en línea:https: //doi.org/10.3332/ecancer.2024.1708
https://hdl.handle.net/20.500.14703/400
Access Level:acceso abierto
Palabra clave:breast cancer
cost
HER2 positive
intravenous
Peru
subcutaneous
Trastuzumab
https://purl.org/pe-repo/ocde/ford#3.02.21
Descripción
Sumario:Breast cancer (BC) is a global concern, with Peru experiencing a high incidence and mortality. Trastuzumab, a crucial treatment for human epidermal growth factor receptor 2-positive BC, is administered intravenously or subcutaneously (SC). This study evaluates the costs associated with both methods at Peru's Instituto Nacional de Enfermedades Neoplásicas. Real data indicate that SC administration reduces treatment costs by approximately S/15,049.09. Cross-continental comparisons highlight a global trend favouring SC administration for efficiency and cost-effectiveness. The analysis provides insights for informed decision-making in resource-constrained healthcare settings like Peru, emphasising the need to consider local contexts in optimising oncology care.