Oxydative stress, endothelial dysfunction and atheroesclerosis

Many of the cardiovascular diseases pathologic components are closely related to reactive oxygen species (ROS) metabolism deregulation (oxidative stress). For example, LDL oxidation, endothelial dysfunction and inflammatory processes are partially mediated by increase of cellular ROS production. Oth...

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Detalles Bibliográficos
Autor: Lara Terán, Joffre
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:Perú
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Idioma:español
OAI Identifier:oai:revistasinvestigacion.unmsm.edu.pe:article/10856
Acceso en línea:https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/10856
Access Level:acceso abierto
Palabra clave:Reactive oxygen species
cell
Especies reactivas de oxígeno
célula
Descripción
Sumario:Many of the cardiovascular diseases pathologic components are closely related to reactive oxygen species (ROS) metabolism deregulation (oxidative stress). For example, LDL oxidation, endothelial dysfunction and inflammatory processes are partially mediated by increase of cellular ROS production. Other conditions associated with cardiovascular disease as insulin resistance and metabolic syndrome are also characterized by ROS overproduction and excessive oxidative stress. In this article ROS participation in these pathologic processes is reviewed.