Effect of human bone lyophilized graft and human lyophilized amniotic membrane on bone regeneration of rabbit tibias

This study aimed to investigate the effect of lyophilized human bone graft in combination with lyophilized human amniotic membrane in bone regeneration of rabbit tibias. Methodology: It were used 10 New Zealand male and female white rabbits 6 to 9 months of age, in good condition, weighing 3.5 kg-4...

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Detalles Bibliográficos
Autor: Paredes Nomberto, Frank
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Perú
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Idioma:español
OAI Identifier:oai:revistasinvestigacion.unmsm.edu.pe:article/11519
Acceso en línea:https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/11519
Access Level:acceso abierto
Palabra clave:Human bone graft lyophilized
amniotic membrane
bone regeneration.
Injerto óseo humano liofilizado
membrana amniótica
regeneración ósea.
Descripción
Sumario:This study aimed to investigate the effect of lyophilized human bone graft in combination with lyophilized human amniotic membrane in bone regeneration of rabbit tibias. Methodology: It were used 10 New Zealand male and female white rabbits 6 to 9 months of age, in good condition, weighing 3.5 kg-4 kg. Two circular bone defects 4mm diameter were created in the lower región of the tibias. One of the defects made belonged to control group and was only covered with amniotic membrane, the other defect belonged to the experimental group and was covered with lyophilized human graft plus lyophilized amniotic membrane as a barrier. The animals were sacrificed at 16 weeks after surgery and a clinical and histological analysis of the area of bone defects was done. It was concluded that bone regeneration was significantly higher in the defects covered with lyophilized human bone in combination with amniotic membrane than the control group which took only amniotic membrane as a barrier.