Ileal neuroendocrine tumor with carcinoid syndrome, neoplasia of difficult diagnosis and variable prognosis.

The neuroendocrine tumor (NET) is of difficult diagnosis due to nonspecific symptoms; management is also a challenge. We present the case of a 78 year-old male who suffered of chronic upper abdominal pain and was admitted to emergency with intestinal obstruction and symptoms of carcinoid syndrome (C...

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Detalles Bibliográficos
Autores: Miranda, Gonzalo, Luna, Laura
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Perú
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Idioma:español
OAI Identifier:oai:revistasinvestigacion.unmsm.edu.pe:article/11147
Acceso en línea:https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/11147
Access Level:acceso abierto
Palabra clave:Ileal neuroendocrine tumor
carcinoid syndrome
neuroendocrine tumor.
Tumor neuroendocrino ileal
síndrome carcinoide
tumores neuroendocrinos.
Descripción
Sumario:The neuroendocrine tumor (NET) is of difficult diagnosis due to nonspecific symptoms; management is also a challenge. We present the case of a 78 year-old male who suffered of chronic upper abdominal pain and was admitted to emergency with intestinal obstruction and symptoms of carcinoid syndrome (CS). At surgery an ileal tumor was resected with pathology report of NET positive for chromogranin A and ki 67 proliferative index of 2-3%. The patient continued with CS symptoms and presented high levels of 5-HIAA and liver metastases by MRI. Octreotide was started with good outcome. Experience with this case indicates to be alert at symptoms of functioning NET, due to an increase in its incidence. It is useful to request immunohistochemical markers. Identification of NET with low grade mitosis and proliferation signal good prognosis.