Anatomical and histopathological evaluation of the equine jejunal anastomosis coated with bovine pericardium xenograft

The evaluation of the untreated bovine pericardium xenograft as a biomaterial for the lining of the small intestine anastomosis in equines was conducted. Seven horses with ages between 3 and 10 years were operated on. Two of them were randomly selected, doing a laparotomy to one of them at 15 days a...

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Detalhes bibliográficos
Autores: Aguilar G., Ceesar N., Delgado C., Alfredo, Chavera C., Alfonso, Cueva R., Medalí
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:Perú
Recursos:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Idioma:español
OAI Identifier:oai:revistasinvestigacion.unmsm.edu.pe:article/15306
Acesso em linha:https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/15306
Access Level:acceso abierto
Palavra-chave:equine
bovine pericardium
anastomosis
xenograft
enterectomy
small intestine
biomaterial
equino
pericardio bovino
xenoinjerto
enterectomía
intestino delgado
Descrição
Resumo:The evaluation of the untreated bovine pericardium xenograft as a biomaterial for the lining of the small intestine anastomosis in equines was conducted. Seven horses with ages between 3 and 10 years were operated on. Two of them were randomly selected, doing a laparotomy to one of them at 15 days and the other at 100 days post-surgery. In the macroscopic and histopathological studies of the cicatricial area of the end-to-end anastomosis it was evidenced that the xenograft does not contract or move from the line of suture, guaranteeing the process of cicatricial remodeling and avoiding complications such as peritonitis, stenosis, abscesses, anastomotic leakage and adhesions. It is concluded that the untreated bovine pericardium xenograft is viable and effective as a jejunal enterectomy lining, showing good adaptability as a natural microenvironment for progenitor cells responsible for cicatricial remodeling, although it leads to a moderate phlogosis and fibrosis that disappear progressively after the convalescence period, without calcification or collagen degeneration.