TSH-secreting pituitary adenoma in a patient with paranoid schizophrenia: case report
The clinical case of a patient with paranoid schizophrenia and persistent anxiety, associated with central hyperthyroidism due to a pituitary microadenoma, is presented. A 24-year-old male with psychotic symptoms and persistent anxiety with somatic symptoms, receiving therapeutic doses of clozapine...
| Autores: | , , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2025 |
| País: | Perú |
| Recursos: | Universidad Peruana Cayetano Heredia |
| Repositorio: | Revistas - Universidad Peruana Cayetano Heredia |
| Idioma: | español |
| OAI Identifier: | oai:revistas.upch.edu.pe:article/6330 |
| Acesso em linha: | https://revistas.upch.edu.pe/index.php/RNP/article/view/6330 |
| Access Level: | acceso abierto |
| Palavra-chave: | esquizofrenia microadenoma hipofisiario ansiedad tirotropinoma schizophrenia TSH-secreting pituitary adenoma anxiety thyrotropinoma |
| Resumo: | The clinical case of a patient with paranoid schizophrenia and persistent anxiety, associated with central hyperthyroidism due to a pituitary microadenoma, is presented. A 24-year-old male with psychotic symptoms and persistent anxiety with somatic symptoms, receiving therapeutic doses of clozapine and benzodiazepines showed clinical improvement after a joint management approach with the endocrinology department due to central hyperthyroidism. Biochemical hormonal analysis and imaging studies were necessary to diagnose a TSH-secreting pituitary microadenoma (thyrotropinoma), a rare medical condition associated in this case with a severe mental disorder. Interdisciplinary management is essential in clinical contexts where diagnostic uncertainty arises, requiring a comprehensive clinical management. |
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