How we approach conservative treatment of retinoblastoma in South America in the era of local ocular treatments: A consensus of the Grupo America Latina de Oncologia Pediatrica (GALOP)

Local therapies are increasingly used for ocular preservation in retinoblastoma. In middle-income countries, these techniques pose specific challenges mostly related to more advanced disease at diagnosis. The Grupo de America Latina de Oncología Pediátrica (GALOP) developed a consensus document for...

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Bibliographic Details
Authors: Garin, JPL, Sampor, C, Grigorovski, N, Ceciliano, A, Fandiño, A, Ossandon, D, Perez, V, Caixeta, R, Neto, JCA, Alarcon, S, Silva, S, Teixeira, L, Antoneli, CG, Mattosinho, C, Leal-Leal, C, Castela, G, Requejo, F, Catala, J, Macedo, C, Chantada, GL
Format: article
Status:Published version
Publication Date:2023
Country:Perú
Institution:Instituto Nacional de Enfermedades Neoplásicas
Repository:INEN-Institucional
Language:English
OAI Identifier:oai:repositorio.inen.sld.pe:20.500.14703/211
Online Access:https: //doi.org/10.1002/pbc.30352
https://hdl.handle.net/20.500.14703/211
Access Level:Open access
Keyword:intra-arterial chemotherapy
intra-vitreal chemotherapy
retinoblastoma
https://purl.org/pe-repo/ocde/ford#3.02.21
Description
Summary:Local therapies are increasingly used for ocular preservation in retinoblastoma. In middle-income countries, these techniques pose specific challenges mostly related to more advanced disease at diagnosis. The Grupo de America Latina de Oncología Pediátrica (GALOP) developed a consensus document for the management of conservative therapy for retinoblastoma. Intra-arterial chemotherapy (OAC) is the preferred therapy, except for those with less advanced disease or age younger than 6 months. OAC allowed for a reduction in the use of external beam radiotherapy in our setting. Intravitreal chemotherapy is the preferred treatment for vitreous seeding. Enucleation is the treatment of choice for eyes with advanced disease.

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