Blastocyst Transfer In An Oocyte Donation Program: How To Reduce The Multiple Pregnancy Of High Order

Commonly the assisted reproduction technology was based on the transfer of cleavage-stage embryos in day 2 or 3 after oocyte retrieval. However, in the last years is common the embryo transfer in the blastocyst-stage. The aim of the present study was to evaluate the pregnancy and implantation rates...

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Bibliographic Details
Author: Portella Ruiz, Jimmy
Format: article
Status:Published version
Publication Date:2015
Country:Perú
Institution:Universidad de San Martín de Porres
Repository:Revistas - Universidad de San Martín de Porres
Language:Spanish
OAI Identifier:oai:revistas.usmp.edu.pe:article/11
Online Access:https://portalrevistas.aulavirtualusmp.pe/index.php/VJ/article/view/11
Access Level:Open access
Keyword:Embryo
blastocyst
day 3 embryo transfer
day 5 embryo transfer
in vitro fertilization
oocyte donation.
Embrión
blastocisto
transferencia día 3
transferencia día 5
fecundación in vitro
donación de ovocitos.
Description
Summary:Commonly the assisted reproduction technology was based on the transfer of cleavage-stage embryos in day 2 or 3 after oocyte retrieval. However, in the last years is common the embryo transfer in the blastocyst-stage. The aim of the present study was to evaluate the pregnancy and implantation rates when embryo transfer was carried out in cleavage-stage embryos in day 3 or in blastocyst-stage embryos in day 5 in an assisted reproduction program with oocyte donation. 1667 cycles of assisted reproduction were studied retrospectively, 594 cycles with embryo transfer of day 3 and 1073 cycles of day 5. Implantation (29,09 % vs 44,85 %), pregnancy (51,01 % vs 61,7%) and delivery (44,28 % vs 52,19 %) rates were significantly higher with the blastocyst group transfer compared to cleavage-stage embryos group. Instead, the higher-order multiple pregnancy rates were significantly lower with the blastocyst group transfer. In conclusion, the results of this study support the blastocyst transfer in f