Primary Merkel vulvar cell carcinoma

Merkel cells were originally described in the stratum basale of the epidermis withneuroendocrine properties. Merkel cell carcinoma of the vulva is an extremelyrare and highly aggressive neoplasm. There are few cases of these tumors, mostof which have been considered neuroendocrine tumors. The histol...

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Detalles Bibliográficos
Autores: Torres-Cepeda, Duly, Rondon-Tapia, Martha, Reyna-Villasmil, Eduardo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:Perú
Institución:Sociedad Peruana de Obstetricia y Ginecología
Repositorio:Revista Peruana de Ginecología y Obstetricia
Idioma:español
inglés
OAI Identifier:oai:ginecologiayobstetricia.pe:article/2442
Acceso en línea:https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2442
Access Level:acceso abierto
Palabra clave:Vulva
Carcinoma de células de Merkel
Neoplasias de la vulva
Carcinoma
Merkel cell
Vulvar neoplasms
Descripción
Sumario:Merkel cells were originally described in the stratum basale of the epidermis withneuroendocrine properties. Merkel cell carcinoma of the vulva is an extremelyrare and highly aggressive neoplasm. There are few cases of these tumors, mostof which have been considered neuroendocrine tumors. The histologic origin andetiology of this disease are controversial. It is known for his aggressive behaviorand propensity for early diffusion. Because of its rarity in this location, it is unclearwhether it behaves differently from similar skin carcinomas in other locations. A caseof primary vulvar Merkel cell carcinoma is presented. Excisional biopsy examinationrevealed a 4 x 3-centimeter tumor in the posterior third of the left labium majus of thevulva without lymph node involvement. The patient underwent radical vulvectomyand bilateral inguinal lymph node dissection. Postoperative histological evaluationshowed no regional or distant metastases.