Medical and surgical management of moderate-to-severe inflamatory bowel disease

The management of inflammatory bowel disease (IBD) is mainly medical, however, more than 70% of patients with Crohn's disease (CD) and 25% with ulcerative colitis (UC) will require surgery during their lifetime. Objective: To evaluate medical, surgical management and evolution in patients with...

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Detalles Bibliográficos
Autores: Paredes Méndez, Juan Eloy, Junes Pérez, Sonia Irene, Vargas Marcacuzco, Henry Tomas, Alosilla Sandoval, Paulo Anibal, Gutiérrez Córdova, Isamar Benyi, Fernández Luque, Jorge Luis, Ortiz Blanco, Eduardo Alvarado
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Perú
Institución:Sociedad de Gastroenterología del Perú
Repositorio:Revista de Gastroenterología del Perú
Idioma:español
OAI Identifier:oai:ojs.revistagastroperu.com:article/1270
Acceso en línea:https://revistagastroperu.com/index.php/rgp/article/view/1270
Access Level:acceso abierto
Palabra clave:Inflamatory bowel diseases
Surgical procedures
operative
Surgery
Enfermedades inflamatorias intestinales
Procedimientos quirúrgicos operativos
Cirugía
Descripción
Sumario:The management of inflammatory bowel disease (IBD) is mainly medical, however, more than 70% of patients with Crohn's disease (CD) and 25% with ulcerative colitis (UC) will require surgery during their lifetime. Objective: To evaluate medical, surgical management and evolution in patients with moderate-to-severe IBD. Materials and methods: Observational, descriptive, retrospective study from January 2011 to December 2019 in the Gastroenterology Service of the Guillermo Almenara Irigoyen National Hospital, Lima-Peru. Results: Twenty two patients with IBD, 17 with CD and 5 with UC were included. Male predominance (59%). Emergency surgery was performed in 35.2% and 60% of patients with CD and UC, respectively. Stenosis and toxic megacolon were the most frequent indications. According to the type of surgery, hemicolectomy (41%) and intestinal resection (41%) were the most frequently performed in CD, while in UC it was total colectomy (60%). Among the postoperative complications, dehiscence/fistula and intra-abdominal collections were the most frequently reported in CD; whereas in UC it was surgical site infection and adynamic ileus. After surgery, biologics and 5-ASA associated with immunomodulator were the most used treatment in CD and UC, respectively. Mortality was 17.6% in CD and 60% in UC. Conclusions: Surgical treatment is an option in the management of moderate-to-severe IBD. Emergency surgery in IBD continues to have a high morbidity and mortality rate.