Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru

Fascioliasis is a worldwide emerging snail-borne zoonotic trematodiasis with a great spreading capacity linked to animal and human movements, climate change, and anthropogenic modifications of freshwater environments. South America is the continent with more human endemic areas caused by Fasciola he...

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Autores: Bardales-Valdivia, J.N., Bargues, M.D., Hobán-Vergara, C., Bardales-Bardales, C., Goicochea-Portal, C., Bazán-Zurita, H., Del Valle-Mendoza, J., Ortiz-Oblitas, P., Más-Coma, S.
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2021
País:Perú
Recursos:Universidad Nacional de Cajamarca
Repositório:UNC-Institucional
Idioma:inglês
OAI Identifier:oai:repositorio.unc.edu.pe:20.500.14074/9537
Acesso em linha:http://hdl.handle.net/20.500.14074/9537
http://dx.doi.org/10.1016/j.onehlt.2021.100265
Access Level:Acceso aberto
Palavra-chave:Human and animal fascioliasis
Galba truncatula
Lymnaea schirazensis
Pseudosuccinea
columella
rDNA ITS-2 sequencing
Cajamarca hyperendemic area
Peru
https://purl.org/pe-repo/ocde/ford#4.00.00
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spelling 2026-02-07T23:32:25Z2026-02-07T23:32:25Z2021-12-19http://hdl.handle.net/20.500.14074/9537http://dx.doi.org/10.1016/j.onehlt.2021.100265Fascioliasis is a worldwide emerging snail-borne zoonotic trematodiasis with a great spreading capacity linked to animal and human movements, climate change, and anthropogenic modifications of freshwater environments. South America is the continent with more human endemic areas caused by Fasciola hepatica, mainly in high altitude areas of Andean regions. The Peruvian Cajamarca area presents the highest human prevalences reported, only lower than those in the Bolivian Altiplano. Sequencing of the complete rDNA ITS-2 allowed for the specific and haplotype classification of lymnaeid snails collected in seasonal field surveys along a transect including 2007–3473 m altitudes. The species Galba truncatula (one haplotype preferentially in higher altitudes) and Pseudosuccinea columella (one haplotype in an isolated population), and the non-transmitting species Lymnaea schirazensis (two haplotypes mainly in lower altitudes) were found. Climatic seasonality proved to influence G. truncatula populations in temporarily dried habitats, whereas L. schirazensis appeared to be more climatologically independent due to its extreme amphibious ecology. Along the southeastern transect from Cajamarca city, G. truncatula and L. schirazensis shared the same site in 7 localities (46.7% of the water collections studied). The detection of G. truncatula in 11 new foci (73.3%), predominantly in northern localities closer to the city, demonstrate that the Cajamarca transmission risk area is markedly wider than previously considered. Lymnaea schirazensis progressively increases its presence when moving away from the city. Results highlight the usefulness of lymnaeid surveys to assess borders of the endemic area and inner distribution of transmission foci. Similar lymnaeid surveys are still in need to be performed in the wide northern and western zones of the Cajamarca city. The coexistence of more than one lymnaeid transmitting species, together with a morphologically indistinguishable non-transmitting species and livestock movements inside the area, conform a complex scenario which poses difficulties for the needed One Health control intervention.Este trabajo fue financiado por el (SAF2010–20805); (20805, SAF2010); (RD16/0027/0023); Ministerio de Economía y Competitividad, MINECO; Generalitat Valenciana, GVA; Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica, CONCYTECapplication/pdfengElsevier B.V.PEhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85106236370&doi=10.1016%2Fj.onehlt.2021.100265&partnerID=40&md5=b1781813411c3cc2fc9c5a938d1c0426One Health 13,100265info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Human and animal fascioliasisGalba truncatulaLymnaea schirazensisPseudosuccineacolumellarDNA ITS-2 sequencingCajamarca hyperendemic areaPeruhttps://purl.org/pe-repo/ocde/ford#4.00.00Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peruinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionreponame:UNC-Institucionalinstname:Universidad Nacional de Cajamarcainstacron:UNCBardales-Valdivia, J.N.Bargues, M.D.Hobán-Vergara, C.Bardales-Bardales, C.Goicochea-Portal, C.Bazán-Zurita, H.Del Valle-Mendoza, J.Ortiz-Oblitas, P.Más-Coma, S.ORIGINALmain.pdfmain.pdfapplication/pdf1442755http://repositorio.unc.edu.pe/bitstream/20.500.14074/9537/1/main.pdfba3b8c7bf699045d37aae3157badc6faMD5120.500.14074/9537oai:repositorio.unc.edu.pe:20.500.14074/95372026-02-07 18:32:31.2Universidad Nacional de Cajamarcarepositorio@unc.edu.pe
dc.title.es_PE.fl_str_mv Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru
title Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru
spellingShingle Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru
Bardales-Valdivia, J.N.
Human and animal fascioliasis
Galba truncatula
Lymnaea schirazensis
Pseudosuccinea
columella
rDNA ITS-2 sequencing
Cajamarca hyperendemic area
Peru
https://purl.org/pe-repo/ocde/ford#4.00.00
title_short Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru
title_full Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru
title_fullStr Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru
title_full_unstemmed Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru
title_sort Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru
dc.creator.none.fl_str_mv Bardales-Valdivia, J.N.
Bargues, M.D.
Hobán-Vergara, C.
Bardales-Bardales, C.
Goicochea-Portal, C.
Bazán-Zurita, H.
Del Valle-Mendoza, J.
Ortiz-Oblitas, P.
Más-Coma, S.
author Bardales-Valdivia, J.N.
author_facet Bardales-Valdivia, J.N.
Bargues, M.D.
Hobán-Vergara, C.
Bardales-Bardales, C.
Goicochea-Portal, C.
Bazán-Zurita, H.
Del Valle-Mendoza, J.
Ortiz-Oblitas, P.
Más-Coma, S.
author_role author
author2 Bargues, M.D.
Hobán-Vergara, C.
Bardales-Bardales, C.
Goicochea-Portal, C.
Bazán-Zurita, H.
Del Valle-Mendoza, J.
Ortiz-Oblitas, P.
Más-Coma, S.
author2_role author
author
author
author
author
author
author
author
dc.subject.es_PE.fl_str_mv Human and animal fascioliasis
Galba truncatula
Lymnaea schirazensis
Pseudosuccinea
columella
rDNA ITS-2 sequencing
Cajamarca hyperendemic area
Peru
topic Human and animal fascioliasis
Galba truncatula
Lymnaea schirazensis
Pseudosuccinea
columella
rDNA ITS-2 sequencing
Cajamarca hyperendemic area
Peru
https://purl.org/pe-repo/ocde/ford#4.00.00
dc.subject.ocde.es_PE.fl_str_mv https://purl.org/pe-repo/ocde/ford#4.00.00
description Fascioliasis is a worldwide emerging snail-borne zoonotic trematodiasis with a great spreading capacity linked to animal and human movements, climate change, and anthropogenic modifications of freshwater environments. South America is the continent with more human endemic areas caused by Fasciola hepatica, mainly in high altitude areas of Andean regions. The Peruvian Cajamarca area presents the highest human prevalences reported, only lower than those in the Bolivian Altiplano. Sequencing of the complete rDNA ITS-2 allowed for the specific and haplotype classification of lymnaeid snails collected in seasonal field surveys along a transect including 2007–3473 m altitudes. The species Galba truncatula (one haplotype preferentially in higher altitudes) and Pseudosuccinea columella (one haplotype in an isolated population), and the non-transmitting species Lymnaea schirazensis (two haplotypes mainly in lower altitudes) were found. Climatic seasonality proved to influence G. truncatula populations in temporarily dried habitats, whereas L. schirazensis appeared to be more climatologically independent due to its extreme amphibious ecology. Along the southeastern transect from Cajamarca city, G. truncatula and L. schirazensis shared the same site in 7 localities (46.7% of the water collections studied). The detection of G. truncatula in 11 new foci (73.3%), predominantly in northern localities closer to the city, demonstrate that the Cajamarca transmission risk area is markedly wider than previously considered. Lymnaea schirazensis progressively increases its presence when moving away from the city. Results highlight the usefulness of lymnaeid surveys to assess borders of the endemic area and inner distribution of transmission foci. Similar lymnaeid surveys are still in need to be performed in the wide northern and western zones of the Cajamarca city. The coexistence of more than one lymnaeid transmitting species, together with a morphologically indistinguishable non-transmitting species and livestock movements inside the area, conform a complex scenario which poses difficulties for the needed One Health control intervention.
publishDate 2021
dc.date.accessioned.none.fl_str_mv 2026-02-07T23:32:25Z
dc.date.available.none.fl_str_mv 2026-02-07T23:32:25Z
dc.date.issued.fl_str_mv 2021-12-19
dc.type.es_PE.fl_str_mv info:eu-repo/semantics/article
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format article
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dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.14074/9537
dc.identifier.doi.es_PE.fl_str_mv http://dx.doi.org/10.1016/j.onehlt.2021.100265
url http://hdl.handle.net/20.500.14074/9537
http://dx.doi.org/10.1016/j.onehlt.2021.100265
dc.language.iso.es_PE.fl_str_mv eng
language eng
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One Health 13,100265
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instname_str Universidad Nacional de Cajamarca
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institution UNC
reponame_str UNC-Institucional
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