Brown tumor in the mandible as an initial presentation of primary hyperparathyroidism

Brown tumor (TP) is a benign bone lesion caused by excess osteoclastic activity and hemosiderin deposition as a result of primary or secondary hyperparathyroidism. We present the case of a 71-year-old male patient with a mandibular tumor and bone pain in the lower limbs. He was initially evaluated b...

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Detalles Bibliográficos
Autor: Miranda Manrique, Gonzalo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:Perú
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Idioma:español
OAI Identifier:oai:revistasinvestigacion.unmsm.edu.pe:article/27415
Acceso en línea:https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/27415
Access Level:acceso abierto
Palabra clave:Mandible
Hyperparathyroidism
Neoplasms
Mandíbula
Hiperparatiroidismo
Neoplasias
Descripción
Sumario:Brown tumor (TP) is a benign bone lesion caused by excess osteoclastic activity and hemosiderin deposition as a result of primary or secondary hyperparathyroidism. We present the case of a 71-year-old male patient with a mandibular tumor and bone pain in the lower limbs. He was initially evaluated by the head and neck department who performed excision of mandibular lesion with histological result of giant cells with necrotic and hemorrhagic areas. 3 months later, hypercalcemia was evident, and he was referred to the endocrinology department. The diagnosis of primary hyperparathyroidism associated with skeletal complications was confirmed and parathyroidectomy was scheduled with histological confirmation of parathyroid adenoma. The present case is of interest because of the initial presentation of primary hyperparathyroidism associated with the presence of a brown tumor as a differential diagnosis when evaluating a patient with mandibular bone tumor.