Effect of platelet-rich plasma on alveolar bone repair following impacted third molar surgery evaluated to Cone Beam computerized tomography

Introduction: Platelet-rich plasma (PRP) is a biomaterial with a high platelets concentration and growth factors enhance tissue regeneration after application in surgical procedures, such as third molar extraction. Material and methods: The study was performed with 20 patients with indication for th...

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Detalles Bibliográficos
Autores: Quincho-Rosales, Dilmer A., Evaristo-Chiyong, Teresa, Portocarrero-Gallardo, Marina G., Churampi-Mancilla, Dalia V., Chui-Galván, Sergio, Grados-Pomarino, Sixto
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Perú
Institución:Fundación Instituto Hipólito Unanue
Repositorio:Diagnóstico
Idioma:español
OAI Identifier:oai:revistadiagnostico.fihu.org.pe:article/283
Acceso en línea:https://revistadiagnostico.fihu.org.pe/index.php/diagnostico/article/view/283
Access Level:acceso abierto
Palabra clave:Plasma rico en plaquetas
tercer molar
regeneración ósea
Plaleth rich plasma
thrid molar
bone healing
Descripción
Sumario:Introduction: Platelet-rich plasma (PRP) is a biomaterial with a high platelets concentration and growth factors enhance tissue regeneration after application in surgical procedures, such as third molar extraction. Material and methods: The study was performed with 20 patients with indication for third bilateral lower molar extraction. The extraction were performed in the same surgical time and one of them the PRP gel was applied (randomly chose) and the other as control group. The postoperative evaluation was carried out until three and a half months, the parameters evaluated were: postoperative pain and wound and bone density using Cone Beam computed tomography. Results: Postoperative pain during the third day, first and second week was lower grade than sites of PRP application to the control group (p <0.05). The bone density measured by Cone Beam CT was higher at the sites of PRP application than the control group (p <0.05). Conclusion: PRP has an effect in reducing postoperative pain and accelerating wound healing, and it also shows higher bone density compared to not applying PRP.