Effect of delayed recanalization of occluded acute myocardial infarction-related artery using coronary angioplasty on late potentials

Recent evidence suggests that late reperfusion of an occluded infarct-related artery (IRA) after acute myocardial acute infarction (MAI), may reduce the frecuency of subsequent arrhythmic events and sudden death. Mechanical reperfusion of an occluded IRA, performing percutaneous trasluminal coronary...

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Detalhes bibliográficos
Autor: Horna, Manuel
Formato: artículo
Estado:Versión publicada
Fecha de publicación:1996
País:Perú
Recursos:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Idioma:español
OAI Identifier:oai:revistasinvestigacion.unmsm.edu.pe:article/4739
Acesso em linha:https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/4739
Access Level:acceso abierto
Palavra-chave:Reperfucion
angioplasty
myocardial infarction
Reperfusión
Angioplastia
Infarto de Miocardio
Descrição
Resumo:Recent evidence suggests that late reperfusion of an occluded infarct-related artery (IRA) after acute myocardial acute infarction (MAI), may reduce the frecuency of subsequent arrhythmic events and sudden death. Mechanical reperfusion of an occluded IRA, performing percutaneous trasluminal coronary angioplasty (PTCA) 48 to 2 weeks after MAI, has a big success rate, and low symptomatic restenosis. Twenty subjects (19 men and 1 women, aged 32 to 77 year) with a first MAI, signal-averaged electrocardiographic (SAECG), and an occluded IRA were prospectively identified. Late potentials were present in 14 patients after MAI. Eighteenth had a successful PTCA of the occluded IRA, 6 to 32 days after MAI. Follow-up SAECG was performed 1 to 8 days later. In the subgroup of 12 patients with successful reperfusion with an abnormal SAECG before PTCS, 7 (58,3%) showed resolution of late potentials at follow-up, the filtered QRS duration showed a significant reduction (112,1 ± 14,2 msec to 96,7 ± 12,6 msec, p=0,02), and there was a tendency for the root-mean-square voltage to increase and the duration of low amplitude signals < 40 µV to decrease after angioplasty. In contrast 2 patients with late potentials before PTCA and usuccessful reperfusion of the culprit vessel way reduce the incidence of abnormalities on the SAECG, if thhis will result in improved longterm survival awaits confirmations in a large trial.