Growing ovarian teratoma syndrome: Case report and literature review

The growing teratoma syndrome (GTS) is a rare condition in which patients with germ cell tumors present an increase in tumor size or the appearance of new lesions, during or after chemotherapy. The hallmark of this tumor is the unique presence of mature teratoma components, as well as tumor marker v...

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Detalles Bibliográficos
Autores: Alzamora, Maria Claudia, Portugal, Karem, Ortiz, Nazario, Lugon, Julia, Sinchi Roca, Tania, Diaz, Niccole, Venegas, Gino
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:Perú
Institución:Sociedad Peruana de Obstetricia y Ginecología
Repositorio:Revista Peruana de Ginecología y Obstetricia
Idioma:español
inglés
OAI Identifier:oai:ginecologiayobstetricia.pe:article/2294
Acceso en línea:https://ginecologiayobstetricia.pe/index.php/RPGO/article/view/2294
Access Level:acceso abierto
Palabra clave:Neoplasm
Germ Cell
Embryonal cell
Teratoma
Peru
Neoplasia
Células germinales
Células embrionarias
Perú
Descripción
Sumario:The growing teratoma syndrome (GTS) is a rare condition in which patients with germ cell tumors present an increase in tumor size or the appearance of new lesions, during or after chemotherapy. The hallmark of this tumor is the unique presence of mature teratoma components, as well as tumor marker values that become negative with chemotherapy, and remain low thereafter. We report the case of a 28-yearold female who presented a mixed germ cell tumor of the ovary, for which she underwent surgery and subsequent chemotherapy. Later, she developed multiple pelvic tumors that corresponded to mature teratoma. It was crucial in this patient to identify the syndrome to avoid additional treatment with chemotherapy.