Partial characterization and antimicrobial spectrum of inhibitory substances from marine Alteromonas

Inhibitory substances produced by marine strains belonging to the genus Alteromonas spp. are partially characterized. Precipitation of raw extracts supernatans from strains N22.C and N11.6 with concentration saturants of ammonium sulfate and filtrates in columns Sephadex G-25 show the production of...

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Detalhes bibliográficos
Autores: León, Jorge, Tapia, Guillermina
Formato: artículo
Estado:Versión publicada
Fecha de publicación:1999
País:Perú
Recursos:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Idioma:español
OAI Identifier:oai:revistasinvestigacion.unmsm.edu.pe:article/8304
Acesso em linha:https://revistasinvestigacion.unmsm.edu.pe/index.php/rpb/article/view/8304
Access Level:acceso abierto
Palavra-chave:bacterias marinas
actividad inhibitoria
substancia extracelular
Alteromonas
antibiosis.
marine bacteria
inhibitory substances
extracellular substance
Descrição
Resumo:Inhibitory substances produced by marine strains belonging to the genus Alteromonas spp. are partially characterized. Precipitation of raw extracts supernatans from strains N22.C and N11.6 with concentration saturants of ammonium sulfate and filtrates in columns Sephadex G-25 show the production of inhibitory substances (SI) of proteinacea nature. Other assays revealed that these substances have a wide spectrum of antibiotic activity against collection strains pathogens of fish, mollusks and crustaceans. Also, it shows those SI to be thermosensitive at 90 9C for 45 min and stable within the pH range of 3,0 at 9,0 for 15 min. Antibiotic activity of the substances against Vibrio angufflarum NCMB 2133, V anguillarum ATCC 19264 and Aeromonas salmonicida 76,79 was comparatively equivalent to 30 ppm of the antibiotic oxitetraciclina (OTC).