Development of islets of Langerhans in pancreas of neonatal alpacas

The aim of this study was to determine the postnatal development of Islets of Langerhans (IL) in alpacas of 0 to 45 days of age. The animals were divided in nine age groups with range of five days. The mumber of IL varied from 3.03 to 4.46 in 10x fields (with an ocular of 10x), the IL diameter varie...

Descripción completa

Detalles Bibliográficos
Autores: Rodríguez G., José, Espinoza B., Juan, Rojas Z., Gabriela, Lira M., Boris, Vásquez C., María, López-Torres, Bernardo, Caro M., César
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Perú
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Idioma:español
OAI Identifier:oai:revistasinvestigacion.unmsm.edu.pe:article/11171
Acceso en línea:https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/11171
Access Level:acceso abierto
Palabra clave:endocrine pancreas
baby alpaca
neonatal development
páncreas endocrino
crías de alpaca
desarrollo neonatal
Descripción
Sumario:The aim of this study was to determine the postnatal development of Islets of Langerhans (IL) in alpacas of 0 to 45 days of age. The animals were divided in nine age groups with range of five days. The mumber of IL varied from 3.03 to 4.46 in 10x fields (with an ocular of 10x), the IL diameter varied from 67.89 to 72.55 μm, the number of β cells in the IL from 23.79 to 47.08 and other cells from 18.15 to 39.93. Moreover, the insulin receptor and the transport protein GLUT-2 were observed by immunohistochemistry on the first day of life. It is concluded that the number and size of IL increased with age (p<0.05) while β cells do not show the same trend.