Cytomegalovirus hepatitis in a 2-month-old infant: a case report

Congenital cytomegalovirus infection is a cause of neonatal infection that can be asymptomatic; however, its complications are possible in some organs such as the nervous system and the liver. We report a case of a 2-month-old female infant with cytomegalovirus hepatitis characterized by abdominal d...

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Detalles Bibliográficos
Autores: Panez-Gallardo, Jhoana Katherine, Atamari-Anahui, Noé, Limache-Ontiveros, Yesenia, Ccorahua-Rios, Maycol Suker, Miranda-Abarca, Iveth, Orellana-Siuce, Carlos A., Cabrera-Enríquez, John A.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Perú
Institución:Sociedad de Gastroenterología del Perú
Repositorio:Revista de Gastroenterología del Perú
Idioma:español
OAI Identifier:oai:ojs.revistagastroperu.com:article/1272
Acceso en línea:https://revistagastroperu.com/index.php/rgp/article/view/1272
Access Level:acceso abierto
Palabra clave:Cytomegalovirus
Infant
Hepatitis
Peru
Citomegalovirus
Lactante
Perú
Descripción
Sumario:Congenital cytomegalovirus infection is a cause of neonatal infection that can be asymptomatic; however, its complications are possible in some organs such as the nervous system and the liver. We report a case of a 2-month-old female infant with cytomegalovirus hepatitis characterized by abdominal distention, cholestasis, irritability, and poor breastfeeding. In the tests, liver involvement, periventricular microcalcifications, and sensorineural hearing loss were found. The diagnosis was determined by serum antibodies, confirmed with viral load in blood, urine, and liver tissue. Treatment with ganciclovir, vitamin K, and ursodeoxycholic acid was administered with adequate evolution. Cytomegalovirus hepatitis is a complication that may be associated with the involvement of other organs. Antiviral treatment for liver involvement is still controversial; however, it is recommended in children under one month of age if it is associated with neurological damage.