Vitamin D deficiency associated with hyperphosphatemia in children
Children with vitamin D deficiency can have normal or high phosphorus despite having a high parathyroid hormone test (PTH). Pseudohypoparathyroidism (PHP) is characterized by hyperphosphatemia. The similarity that can occur between vitamin D deficiency associated with hyperphosphatemia and PHP makes...
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | Perú |
| Institución: | Colegio Médico del Perú |
| Repositorio: | Acta Médica Peruana |
| Idioma: | español |
| OAI Identifier: | oai:amp.cmp.org.pe:article/1909 |
| Acceso en línea: | https://amp.cmp.org.pe/index.php/AMP/article/view/1909 |
| Access Level: | acceso abierto |
| Palabra clave: | Vitamina D Deficiencia de Vitamina D Hiperfosfatemia Raquitismo Seudohipoparatiroidismo Hormona Paratiroidea Hipocalcemia Niño Vitamin D Vitamin D Deficiency Hyperphosphatemia Rickets Pseudohypoparathyroidism Parathyroid Hormone Hypocalcemia Child |
| Sumario: | Children with vitamin D deficiency can have normal or high phosphorus despite having a high parathyroid hormone test (PTH). Pseudohypoparathyroidism (PHP) is characterized by hyperphosphatemia. The similarity that can occur between vitamin D deficiency associated with hyperphosphatemia and PHP makes it important to review case reports of vitamin D deficiency associated with hyperphosphatemia to understand why this association may occur and what is the relevance of studying the vitamin D level in children with suspected PHP. The aim of this review was to identify reports of children with vitamin D deficiency associated with hyperphosphatemia and to discuss the mechanisms of this association. Reports of 7 children cases were identified. Vitamin D deficiency could reduce the phosphaturic response to elevated PTH. It is concluded that it is important to rule out vitamin D deficiency in all children with suspected PHP |
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