Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts

Objective: Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them. Results: A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-thir...

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Detalhes bibliográficos
Autores: del Valle-Mendoza, Juana, del Valle-Vargas, Cristina, Cieza-Mora, Erico, Martins-Luna, Johanna, Aquino-Ortega, Ronald, Silva-Vásquez, Andrea, Bazán-Mayra, Jorge, Weilg, Pablo, Silva-Caso, Wilmer, Aguilar-Luis, Miguel Angel
Tipo de documento: artigo
Data de publicação:2018
País:Perú
Recursos:Universidad Peruana de Ciencias Aplicadas
Repositório:UPC-Institucional
Idioma:inglês
OAI Identifier:oai:repositorioacademico.upc.edu.pe:10757/624653
Acesso em linha:https://doi.org/10.1186/s13104-018-3405-7
http://hdl.handle.net/10757/624653
Access Level:Acceso aberto
Palavra-chave:Bordetella pertussis
PCR
Pertussis
Whooping cough
Descrição
Resumo:Objective: Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them. Results: A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-third of them were from infants between 2 and 3 months old. The most common symptoms were paroxysms of coughing (88.9%), difficulty breathing (72.2%), cyanosis (77.8%) and fever (50%). The mother was the most common symptomatic carrier (27.8%), followed by uncles/aunts (22.2%) among children with pertussis.