Intralesional corticosteroid injection as a conservative treatment for central giant cell granuloma: a review of the literature

Central giant cell granuloma (CGCG) is a benign intraosseous lesion of the jaws. Traditionally, surgery is the most used treatment for this type of pathology, however, in recent years the use of intralesional corticosteroids injections has been proposed as a conservative alternative. The aim of this...

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Detalles Bibliográficos
Autores: Villarreal Arizpe, Karen Lissette, Guerra Leal, Daniel Alejandro
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Perú
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Idioma:español
OAI Identifier:oai:revistasinvestigacion.unmsm.edu.pe:article/19899
Acceso en línea:https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/19899
Access Level:acceso abierto
Palabra clave:Granuloma
Giant Cell
Injections intralesional
Corticosteroids
Triamcinolone
(source: MeSH NLM)
Células gigantes
Inyecciones intralesiones
Corticoesteroides
Triamcinolona
(fuente: DeCS BIREME)
Descripción
Sumario:Central giant cell granuloma (CGCG) is a benign intraosseous lesion of the jaws. Traditionally, surgery is the most used treatment for this type of pathology, however, in recent years the use of intralesional corticosteroids injections has been proposed as a conservative alternative. The aim of this study is to carry out a bibliographic review of the cases treated with corticosteroids. The author used PubMed and Google Scholar platforms were used to search for articles published between 1994 and 2020, related to CGCG and its treatment with corticosteroids. The results of this research were 28 articles and one abstract were found with 61 patients in total; in most cases, weekly intralesional injections of triamcinolone acetonide with anesthetic were used for 6 weeks, although protocol variants were reported. Of the 61 cases, 38 had complete resolution while the other cases required additional surgical treatment. From this, it seems that the use of intralesional triamcinolone injections have a positive effect in the treatment of CGCG by allowing a complete resolution of the lesion or a decrease in its size, so that subsequent surgery is more conservative.