No Complicated Ectopic Pregnancy: Medical Management With Methotrexate In The Maternal Perinatal National Institute

Objective. To determine the characteristics of medical management with methotrexate in unruptured ectopic pregnancy in Instituto Nacional Materno Perinatal in Lima. Material and methods. A descriptive study, retrospective, realized between January 2009 and December 2010. These were 30 patients diagn...

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Authors: admin, admin, Zambrano-Gamboa, Christian Arturo, Ticona-Huamaní, Mirasol Pavel, Murga-López, Agustín, Carpio-Guzmán, Luis Alberto
Format: article
Status:Published version
Publication Date:2018
Country:Perú
Institution:Instituto Nacional Materno Perinatal
Repository:Revista Peruana de Investigación Materno Perinatal
Language:Spanish
OAI Identifier:oai:investigacionmaternoperinatal.inmp.gob.pe:article/6
Online Access:https://investigacionmaternoperinatal.inmp.gob.pe/index.php/rpinmp/article/view/6
Access Level:Open access
Keyword:Embarazo ectópico
Metotrexate
Ectopic pregnancy
Methotrexate
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spelling No Complicated Ectopic Pregnancy: Medical Management With Methotrexate In The Maternal Perinatal National InstituteEmbarazo Ectópico No Complicado: Manejo Médico con Metotrexate en el INMP. Enero 2009 - Diciembre 2010admin, adminZambrano-Gamboa, Christian ArturoTicona-Huamaní, Mirasol PavelMurga-López, AgustínCarpio-Guzmán, Luis AlbertoEmbarazo ectópicoMetotrexateEctopic pregnancyMethotrexateObjective. To determine the characteristics of medical management with methotrexate in unruptured ectopic pregnancy in Instituto Nacional Materno Perinatal in Lima. Material and methods. A descriptive study, retrospective, realized between January 2009 and December 2010. These were 30 patients diagnosed with unruptured ectopic pregnancy who received methotrexate in the study period. The instrument used was a data collection form developed for study purposes. Results. The most frequent was tubal right at the 56,7% of cases, the most widely used protocol was single-dose in 86,6 % of cases, the most common size was 20 to 35 mm in 60 % of cases, 70 % of cases became negative B-hCG (fraction B of human chorionic gonadotropin), 30% required surgery, the most frequent adverse reaction to methotrexate was nausea (10% of cases).Conclusions. Medical management with methotrexate is an alternative for patients with unruptured ectopic pregnancy, became negative B-hCG (70%). There was no statistically significant differences in the values of the B-hCG at the time of surgical decision.The most widely used protocol was single-dose and route of administration was intramuscularly in all patients.Objetivo. Determinar las características del manejo médico con metotrexate en el embarazo ectópico no complicado en el Instituto Nacional Materno Perinatal de Lima. Materiales y métodos. Estudio tipo Investigación observacional analítica. Diseño: Observacional, descriptivo, retrospectivo, de casos. La muestra estuvo comprendida por 30 historias clínicas, de pacientes con diagnóstico de embarazo ectópico que recibieron metotrexate en el periodo enero 2009 - diciembre 2010. Los instrumentos empleados estuvieron conformados por una ficha de recolección de datos elaborada para los fines de estudio. Resultados. La localización más frecuente fue la tubárica derecha en el 56,7% de los casos, el esquema más usado fue el de la dosis única en el 86,6% de los casos, el tamaño más frecuente fue el de 20 a 35 mm en el 60% de los casos, el 70% de los casos negativizaron la B-hCG (fracción B de la gonadotropina coriónica humana), el 30% requirió cirugía, la reacción adversa más frecuente al metotrexate fue las nauseas (10 % de los casos).Conclusiones. El tratamiento médico con metotrexate es una alternativa para pacientes con embarazo ectópico no complicado, presentando una alta frecuencia de negativización de B-hCG (70 %). No hubo diferencias estadísticamente significativas en cuanto a los valores de la B-hCG al momento de la decisión quirúrgica. El tipo de esquema más usado fue el de una dosis y la vía de administración fue la vía intramuscular en todas las pacientes.Instituto Nacional Materno Perinatal (INMP), Lima - Perú.2018-12-17info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://investigacionmaternoperinatal.inmp.gob.pe/index.php/rpinmp/article/view/610.33421/inmp.20126Revista Peruana de Investigación Materno Perinatal; Vol. 1 No. 1 (2012): Revista Peruana de Investigación Materno Perinatal; 23-28Revista Peruana de Investigación Materno Perinatal; Vol. 1 Núm. 1 (2012): Revista Peruana de Investigación Materno Perinatal; 23-282663-113X2305-3887reponame:Revista Peruana de Investigación Materno Perinatalinstname:Instituto Nacional Materno Perinatalinstacron:INMPspahttps://investigacionmaternoperinatal.inmp.gob.pe/index.php/rpinmp/article/view/6/21Derechos de autor 2022 Revista Peruana de Investigación Materno Perinatalinfo:eu-repo/semantics/openAccessoai:investigacionmaternoperinatal.inmp.gob.pe:article/62022-10-13T06:10:36Z
dc.title.none.fl_str_mv No Complicated Ectopic Pregnancy: Medical Management With Methotrexate In The Maternal Perinatal National Institute
Embarazo Ectópico No Complicado: Manejo Médico con Metotrexate en el INMP. Enero 2009 - Diciembre 2010
title No Complicated Ectopic Pregnancy: Medical Management With Methotrexate In The Maternal Perinatal National Institute
spellingShingle No Complicated Ectopic Pregnancy: Medical Management With Methotrexate In The Maternal Perinatal National Institute
admin, admin
Embarazo ectópico
Metotrexate
Ectopic pregnancy
Methotrexate
title_short No Complicated Ectopic Pregnancy: Medical Management With Methotrexate In The Maternal Perinatal National Institute
title_full No Complicated Ectopic Pregnancy: Medical Management With Methotrexate In The Maternal Perinatal National Institute
title_fullStr No Complicated Ectopic Pregnancy: Medical Management With Methotrexate In The Maternal Perinatal National Institute
title_full_unstemmed No Complicated Ectopic Pregnancy: Medical Management With Methotrexate In The Maternal Perinatal National Institute
title_sort No Complicated Ectopic Pregnancy: Medical Management With Methotrexate In The Maternal Perinatal National Institute
dc.creator.none.fl_str_mv admin, admin
Zambrano-Gamboa, Christian Arturo
Ticona-Huamaní, Mirasol Pavel
Murga-López, Agustín
Carpio-Guzmán, Luis Alberto
author admin, admin
author_facet admin, admin
Zambrano-Gamboa, Christian Arturo
Ticona-Huamaní, Mirasol Pavel
Murga-López, Agustín
Carpio-Guzmán, Luis Alberto
author_role author
author2 Zambrano-Gamboa, Christian Arturo
Ticona-Huamaní, Mirasol Pavel
Murga-López, Agustín
Carpio-Guzmán, Luis Alberto
author2_role author
author
author
author
dc.subject.none.fl_str_mv Embarazo ectópico
Metotrexate
Ectopic pregnancy
Methotrexate
topic Embarazo ectópico
Metotrexate
Ectopic pregnancy
Methotrexate
description Objective. To determine the characteristics of medical management with methotrexate in unruptured ectopic pregnancy in Instituto Nacional Materno Perinatal in Lima. Material and methods. A descriptive study, retrospective, realized between January 2009 and December 2010. These were 30 patients diagnosed with unruptured ectopic pregnancy who received methotrexate in the study period. The instrument used was a data collection form developed for study purposes. Results. The most frequent was tubal right at the 56,7% of cases, the most widely used protocol was single-dose in 86,6 % of cases, the most common size was 20 to 35 mm in 60 % of cases, 70 % of cases became negative B-hCG (fraction B of human chorionic gonadotropin), 30% required surgery, the most frequent adverse reaction to methotrexate was nausea (10% of cases).Conclusions. Medical management with methotrexate is an alternative for patients with unruptured ectopic pregnancy, became negative B-hCG (70%). There was no statistically significant differences in the values of the B-hCG at the time of surgical decision.The most widely used protocol was single-dose and route of administration was intramuscularly in all patients.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-17
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://investigacionmaternoperinatal.inmp.gob.pe/index.php/rpinmp/article/view/6
10.33421/inmp.20126
url https://investigacionmaternoperinatal.inmp.gob.pe/index.php/rpinmp/article/view/6
identifier_str_mv 10.33421/inmp.20126
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://investigacionmaternoperinatal.inmp.gob.pe/index.php/rpinmp/article/view/6/21
dc.rights.none.fl_str_mv Derechos de autor 2022 Revista Peruana de Investigación Materno Perinatal
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 2022 Revista Peruana de Investigación Materno Perinatal
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Nacional Materno Perinatal (INMP), Lima - Perú.
publisher.none.fl_str_mv Instituto Nacional Materno Perinatal (INMP), Lima - Perú.
dc.source.none.fl_str_mv Revista Peruana de Investigación Materno Perinatal; Vol. 1 No. 1 (2012): Revista Peruana de Investigación Materno Perinatal; 23-28
Revista Peruana de Investigación Materno Perinatal; Vol. 1 Núm. 1 (2012): Revista Peruana de Investigación Materno Perinatal; 23-28
2663-113X
2305-3887
reponame:Revista Peruana de Investigación Materno Perinatal
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instacron:INMP
instname_str Instituto Nacional Materno Perinatal
instacron_str INMP
institution INMP
reponame_str Revista Peruana de Investigación Materno Perinatal
collection Revista Peruana de Investigación Materno Perinatal
repository.name.fl_str_mv
repository.mail.fl_str_mv
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