Autofocus algorithm using one dimensional Fourier

A new autofocus algorithm based on one-dimensional Fourier transform and Pearson correlation for Z automatized microscope is proposed. Our goal is to determine in fast response time and accuracy, the best focused plane through an algorithm. We capture in bright and dark field several images set at d...

Descripción completa

Detalles Bibliográficos
Autores: Bueno Ibarra, Mario A., Alvarez Borrego, J., Acho, L.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:México
Institución:Instituto Politécnico Nacional
Repositorio:Repositorio Digital del IPN
OAI Identifier:oai:www.repositoriodigital.ipn.mx:123456789/5617
Acceso en línea:http://www.repositoriodigital.ipn.mx/handle/123456789/5617
Access Level:acceso abierto
Palabra clave:Automated Microscopy
Autofocus,
Fourier Transform
Pearson Correlation
Descripción
Sumario:A new autofocus algorithm based on one-dimensional Fourier transform and Pearson correlation for Z automatized microscope is proposed. Our goal is to determine in fast response time and accuracy, the best focused plane through an algorithm. We capture in bright and dark field several images set at different Z distances from biological organism sample. The algorithm uses the one-dimensional Fourier transform to obtain the image frequency content of a vectors pattern previously defined comparing the Pearson correlation of these frequency vectors versus the reference image frequency vector, the most out of focus image, we find the best focusing. Experimental results showed the algorithm has fast response time and accuracy in getting the best focus plane from captured images. In conclusions, the algorithm can be implemented in real time systems due fast response time, accuracy and robustness. The algorithm can be used to get focused images in bright and dark field and it can be extended to include fusion techniques to construct multifocus final images beyond ofthis paper.