Measurement of blood flow and assessment of breast health by using non-invasive optical techniques

Laser Speckle Imaging (LSI) is an optical technique used to generate blood flow maps with high spatial and temporal resolution. A modified laser speckle imaging (mLSI) enables computation of blood flow maps with relatively high spatial resolution. Although it is known that the sensitivity and noise...

Descripción completa

Detalles Bibliográficos
Autor: NOEMI JASMIN SALAZAR HERMENEGILDO
Tipo de recurso: tesis doctoral
Estado:Versión publicada
Fecha de publicación:2015
País:México
Institución:Instituto Nacional de Astrofísica, Óptica y Electrónica
Repositorio:Repositorio Institucional del INAOE
Idioma:inglés
OAI Identifier:oai:inaoe.repositorioinstitucional.mx:1009/51
Acceso en línea:http://inaoe.repositorioinstitucional.mx/jspui/handle/1009/51
Access Level:acceso abierto
Palabra clave:info:eu-repo/classification/Patrones/Speckle pattern
info:eu-repo/classification/Suma vectorial aleatoria/Random phasor sum
info:eu-repo/classification/Patrones multiples/Multiple Speckle Patterns
info:eu-repo/classification/Velocidad/Velocity of the scatters
info:eu-repo/classification/cti/7
info:eu-repo/classification/cti/33
info:eu-repo/classification/cti/3314
id MX_f2d446cadbbade58abe277b38ecc8e65
oai_identifier_str oai:inaoe.repositorioinstitucional.mx:1009/51
network_acronym_str MX
network_name_str México
repository_id_str
spelling Measurement of blood flow and assessment of breast health by using non-invasive optical techniquesNOEMI JASMIN SALAZAR HERMENEGILDOinfo:eu-repo/classification/Patrones/Speckle patterninfo:eu-repo/classification/Suma vectorial aleatoria/Random phasor suminfo:eu-repo/classification/Patrones multiples/Multiple Speckle Patternsinfo:eu-repo/classification/Velocidad/Velocity of the scattersinfo:eu-repo/classification/cti/7info:eu-repo/classification/cti/33info:eu-repo/classification/cti/3314info:eu-repo/classification/cti/3314Laser Speckle Imaging (LSI) is an optical technique used to generate blood flow maps with high spatial and temporal resolution. A modified laser speckle imaging (mLSI) enables computation of blood flow maps with relatively high spatial resolution. Although it is known that the sensitivity and noise in LSI measurements depend on image exposure time, a fundamental disadvantage of mLSI is that it does not take into account this parameter. In this thesis, the exposure time into the mLSI method was integrated and provides experimental support for this approach with measurements from an in vitro flow phantom. In the other hand it is well known that in LSI, the speckle size must exceed the Nyquist criterion to maximize the speckle’s pattern contrast. The effect of speckle-pixel size ratio not only in dynamic speckle contrast, but also on the calculation of the relative flow speed for temporal and spatial analysis was studied as well. Data suggest that the temporal LSCI algorithm is more accurate at assessing the relative changes in flow speed than the spatial algorithm. Quantify the probabilities for women to develop breast cancer in the future or harbour breast cancer, via their bulk optical tissue properties is the objective of the clinical research in the Ontario Cancer Institute, Canada. As a part of this research, based on measurements of trans-illumination spectroscopy breast tissue from participants of the clinical research, hemoglobin, oxygenated hemoglobin, collagen, lipids and water concentration and the scattering value were obtained by using the equation diffusion in this thesis work.Instituto Nacional de Astrofísica, Óptica y ElectrónicaJULIO CESAR RAMIREZ SAN JUAN2015-11-19info:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://inaoe.repositorioinstitucional.mx/jspui/handle/1009/51reponame:Repositorio Institucional del INAOEinstname:Instituto Nacional de Astrofísica, Óptica y Electrónicainstacron:INAOEengcitation:Salazar-Hermenegildo N.J.info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/4.0oai:inaoe.repositorioinstitucional.mx:1009/512024-08-28T03:22:40Z
dc.title.none.fl_str_mv Measurement of blood flow and assessment of breast health by using non-invasive optical techniques
title Measurement of blood flow and assessment of breast health by using non-invasive optical techniques
spellingShingle Measurement of blood flow and assessment of breast health by using non-invasive optical techniques
NOEMI JASMIN SALAZAR HERMENEGILDO
info:eu-repo/classification/Patrones/Speckle pattern
info:eu-repo/classification/Suma vectorial aleatoria/Random phasor sum
info:eu-repo/classification/Patrones multiples/Multiple Speckle Patterns
info:eu-repo/classification/Velocidad/Velocity of the scatters
info:eu-repo/classification/cti/7
info:eu-repo/classification/cti/33
info:eu-repo/classification/cti/3314
info:eu-repo/classification/cti/3314
title_short Measurement of blood flow and assessment of breast health by using non-invasive optical techniques
title_full Measurement of blood flow and assessment of breast health by using non-invasive optical techniques
title_fullStr Measurement of blood flow and assessment of breast health by using non-invasive optical techniques
title_full_unstemmed Measurement of blood flow and assessment of breast health by using non-invasive optical techniques
title_sort Measurement of blood flow and assessment of breast health by using non-invasive optical techniques
dc.creator.none.fl_str_mv NOEMI JASMIN SALAZAR HERMENEGILDO
author NOEMI JASMIN SALAZAR HERMENEGILDO
author_facet NOEMI JASMIN SALAZAR HERMENEGILDO
author_role author
dc.contributor.none.fl_str_mv JULIO CESAR RAMIREZ SAN JUAN
dc.subject.none.fl_str_mv info:eu-repo/classification/Patrones/Speckle pattern
info:eu-repo/classification/Suma vectorial aleatoria/Random phasor sum
info:eu-repo/classification/Patrones multiples/Multiple Speckle Patterns
info:eu-repo/classification/Velocidad/Velocity of the scatters
info:eu-repo/classification/cti/7
info:eu-repo/classification/cti/33
info:eu-repo/classification/cti/3314
info:eu-repo/classification/cti/3314
topic info:eu-repo/classification/Patrones/Speckle pattern
info:eu-repo/classification/Suma vectorial aleatoria/Random phasor sum
info:eu-repo/classification/Patrones multiples/Multiple Speckle Patterns
info:eu-repo/classification/Velocidad/Velocity of the scatters
info:eu-repo/classification/cti/7
info:eu-repo/classification/cti/33
info:eu-repo/classification/cti/3314
info:eu-repo/classification/cti/3314
description Laser Speckle Imaging (LSI) is an optical technique used to generate blood flow maps with high spatial and temporal resolution. A modified laser speckle imaging (mLSI) enables computation of blood flow maps with relatively high spatial resolution. Although it is known that the sensitivity and noise in LSI measurements depend on image exposure time, a fundamental disadvantage of mLSI is that it does not take into account this parameter. In this thesis, the exposure time into the mLSI method was integrated and provides experimental support for this approach with measurements from an in vitro flow phantom. In the other hand it is well known that in LSI, the speckle size must exceed the Nyquist criterion to maximize the speckle’s pattern contrast. The effect of speckle-pixel size ratio not only in dynamic speckle contrast, but also on the calculation of the relative flow speed for temporal and spatial analysis was studied as well. Data suggest that the temporal LSCI algorithm is more accurate at assessing the relative changes in flow speed than the spatial algorithm. Quantify the probabilities for women to develop breast cancer in the future or harbour breast cancer, via their bulk optical tissue properties is the objective of the clinical research in the Ontario Cancer Institute, Canada. As a part of this research, based on measurements of trans-illumination spectroscopy breast tissue from participants of the clinical research, hemoglobin, oxygenated hemoglobin, collagen, lipids and water concentration and the scattering value were obtained by using the equation diffusion in this thesis work.
publishDate 2015
dc.date.none.fl_str_mv 2015-11-19
dc.type.none.fl_str_mv info:eu-repo/semantics/doctoralThesis
info:eu-repo/semantics/publishedVersion
format doctoralThesis
status_str publishedVersion
dc.identifier.none.fl_str_mv http://inaoe.repositorioinstitucional.mx/jspui/handle/1009/51
url http://inaoe.repositorioinstitucional.mx/jspui/handle/1009/51
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv citation:Salazar-Hermenegildo N.J.
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Nacional de Astrofísica, Óptica y Electrónica
publisher.none.fl_str_mv Instituto Nacional de Astrofísica, Óptica y Electrónica
dc.source.none.fl_str_mv reponame:Repositorio Institucional del INAOE
instname:Instituto Nacional de Astrofísica, Óptica y Electrónica
instacron:INAOE
instname_str Instituto Nacional de Astrofísica, Óptica y Electrónica
instacron_str INAOE
institution INAOE
reponame_str Repositorio Institucional del INAOE
collection Repositorio Institucional del INAOE
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1858177645856948224
score 14.965156