Catalytic nanomedicine for chronic wounds in diabetic patients: physiology, pathophysiology, and a success story

Chronic wounds, especially in diabetes patients, severely impact quality of life. Catalytic Nanomedicine offers hope by designing bionanocatalysts, nanostructures that selectively damage nucleic acids. These nanostructures excel in disinfection, harming microorganisms while preserving healthy tissue...

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Detalles Bibliográficos
Autores: López-Goerne, Tessy, Padilla-Godínez, Francisco Javier, Arévalo, Alba
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:México
Institución:UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO
Repositorio:Mundo Nano. Revista Interdisciplinaria en Nanociencias y Nanotecnología
Idioma:inglés
español
OAI Identifier:oai:ojs.pkp.sfu.ca:article/69817
Acceso en línea:https://www.mundonano.unam.mx/ojs/index.php/nano/article/view/69817
Access Level:acceso abierto
Palabra clave:Catalytic Nanomedicine
chronic wound
diabetes
bionanocatalyst
pathophysiology
catalytic nanomedicine
Descripción
Sumario:Chronic wounds, especially in diabetes patients, severely impact quality of life. Catalytic Nanomedicine offers hope by designing bionanocatalysts, nanostructures that selectively damage nucleic acids. These nanostructures excel in disinfection, harming microorganisms while preserving healthy tissue. They've been used for chronic wound healing, and this study explores their mechanisms and potential in tissue regeneration. The article underscores their significance in broad-spectrum disinfection, even against biofilms. It provides context by comparing glucose regulation in both healthy and diabetic states, with a focus on diabetic foot pathology. Lastly, it highlights a successful case of a diabetic chronic wound treated with Catalytic Nanomedicine to demonstrate its efficacy in promoting wound healing.