Antibacterial Activity of Crude Extract and Purified Acetogenins from Annona muricata Seeds

Artículo

Detalles Bibliográficos
Autores: Aguilar Hernández, Gabriela, López Romero, Brandon A, Pérez Larios, Alejandro, Ruvalcaba Gómez, José M, Castellanos Huerta, Inkar, Tellez Isaias, Guillermo, Petrone García, Victor M, Anaya Esparza, Luis Miguel, Montalvo González, Efigenia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:México
Institución:Universidad de Guadalajara
Repositorio:Repositorio UDG CUALTOS
OAI Identifier:oai:repositorio.cualtos.udg.mx:123456789/1526
Acceso en línea:https://doi.org/10.3390/app13010558
http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1526
Access Level:acceso abierto
Palabra clave:A. muricata
seeds
acetogenins
natural extracts
antimicrobial activity
id MX_e7c6036cd3ffbf3cc72b771e0cd7f8d8
oai_identifier_str oai:repositorio.cualtos.udg.mx:123456789/1526
network_acronym_str MX
network_name_str México
repository_id_str
spelling Antibacterial Activity of Crude Extract and Purified Acetogenins from Annona muricata SeedsAguilar Hernández, GabrielaLópez Romero, Brandon APérez Larios, AlejandroRuvalcaba Gómez, José MCastellanos Huerta, InkarTellez Isaias, GuillermoPetrone García, Victor MAnaya Esparza, Luis MiguelMontalvo González, EfigeniaA. muricataseedsacetogeninsnatural extractsantimicrobial activityArtículoCurrently, several biological activities are attributed to the acetogenins (ACGs) of Annonaceae (including Annona muricata); among these is antimicrobial activity. The main focus of this experiment was to evaluate the antimicrobial effect of the crude extract (CE) and purified acetogenins (P-ACGs) from the endosperm of A. muricata seeds using agar disk diffusion, lethality, sub-lethal, and potential damage membrane tests against Gram-positive and Gram-negative microorganisms. According to the results, P-ACGs present the highest antibacterial effect (12.5–4000 µg/mL) against Enterococcus faecalis (11–15.67 mm), Listeria monocytogenes (12–18 mm), Aeromonas hydrophila (10.33–11.67 mm), Bulkholderia cenocepacia (11–12 mm), and Salmonella paratiphy (11–15.67 mm), and a minimum inhibitory concentration ranging from 0.009 to 12.50 µg/mL. Measurement of the membrane potential shows that, in the presence of P-ACGs, the number of viable cells is reduced, with a significant logarithmic reduction observed (0.38, 1.27, and 1.81 CFU/mL) and a significant sub-lethal lesion (57.78, 96.14, and 98.42%) in Escherichia coli, E. faecalis, and L. monocytogenes, respectively. According to this study, the results demonstrate that P-ACGs from A. muricata seeds are potent and effective antibacterial compounds with potential pharmaceutical applications.Multidisciplinary Digital Publishing Institute2023-06-20T19:46:49Z2023-06-20T19:46:49Z2023-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleAguilar-Hernández G, López-Romero BA, Pérez-Larios A, Ruvalcaba-Gómez JM, Castellanos-Huerta I, Tellez-Isaias G, Petrone-García VM, Anaya-Esparza LM, Montalvo-González E. Antibacterial Activity of Crude Extract and Purified Acetogenins from Annona muricata Seeds. Applied Sciences. 2023; 13(1):558. https://doi.org/10.3390/app130105582076-3417https://doi.org/10.3390/app13010558http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1526reponame:Repositorio UDG CUALTOSinstname:Universidad de Guadalajarainstacron:UDGenApplied Sciences;2023, Vol. 13 (1), 558info:eu-repo/semantics/openAccessoai:repositorio.cualtos.udg.mx:123456789/15262024-10-11T19:20:39Z
dc.title.none.fl_str_mv Antibacterial Activity of Crude Extract and Purified Acetogenins from Annona muricata Seeds
title Antibacterial Activity of Crude Extract and Purified Acetogenins from Annona muricata Seeds
spellingShingle Antibacterial Activity of Crude Extract and Purified Acetogenins from Annona muricata Seeds
Aguilar Hernández, Gabriela
A. muricata
seeds
acetogenins
natural extracts
antimicrobial activity
title_short Antibacterial Activity of Crude Extract and Purified Acetogenins from Annona muricata Seeds
title_full Antibacterial Activity of Crude Extract and Purified Acetogenins from Annona muricata Seeds
title_fullStr Antibacterial Activity of Crude Extract and Purified Acetogenins from Annona muricata Seeds
title_full_unstemmed Antibacterial Activity of Crude Extract and Purified Acetogenins from Annona muricata Seeds
title_sort Antibacterial Activity of Crude Extract and Purified Acetogenins from Annona muricata Seeds
dc.creator.none.fl_str_mv Aguilar Hernández, Gabriela
López Romero, Brandon A
Pérez Larios, Alejandro
Ruvalcaba Gómez, José M
Castellanos Huerta, Inkar
Tellez Isaias, Guillermo
Petrone García, Victor M
Anaya Esparza, Luis Miguel
Montalvo González, Efigenia
author Aguilar Hernández, Gabriela
author_facet Aguilar Hernández, Gabriela
López Romero, Brandon A
Pérez Larios, Alejandro
Ruvalcaba Gómez, José M
Castellanos Huerta, Inkar
Tellez Isaias, Guillermo
Petrone García, Victor M
Anaya Esparza, Luis Miguel
Montalvo González, Efigenia
author_role author
author2 López Romero, Brandon A
Pérez Larios, Alejandro
Ruvalcaba Gómez, José M
Castellanos Huerta, Inkar
Tellez Isaias, Guillermo
Petrone García, Victor M
Anaya Esparza, Luis Miguel
Montalvo González, Efigenia
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv A. muricata
seeds
acetogenins
natural extracts
antimicrobial activity
topic A. muricata
seeds
acetogenins
natural extracts
antimicrobial activity
description Artículo
publishDate 2023
dc.date.none.fl_str_mv 2023-06-20T19:46:49Z
2023-06-20T19:46:49Z
2023-01
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv Aguilar-Hernández G, López-Romero BA, Pérez-Larios A, Ruvalcaba-Gómez JM, Castellanos-Huerta I, Tellez-Isaias G, Petrone-García VM, Anaya-Esparza LM, Montalvo-González E. Antibacterial Activity of Crude Extract and Purified Acetogenins from Annona muricata Seeds. Applied Sciences. 2023; 13(1):558. https://doi.org/10.3390/app13010558
2076-3417
https://doi.org/10.3390/app13010558
http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1526
identifier_str_mv Aguilar-Hernández G, López-Romero BA, Pérez-Larios A, Ruvalcaba-Gómez JM, Castellanos-Huerta I, Tellez-Isaias G, Petrone-García VM, Anaya-Esparza LM, Montalvo-González E. Antibacterial Activity of Crude Extract and Purified Acetogenins from Annona muricata Seeds. Applied Sciences. 2023; 13(1):558. https://doi.org/10.3390/app13010558
2076-3417
url https://doi.org/10.3390/app13010558
http://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1526
dc.language.none.fl_str_mv en
language_invalid_str_mv en
dc.relation.none.fl_str_mv Applied Sciences;2023, Vol. 13 (1), 558
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:Repositorio UDG CUALTOS
instname:Universidad de Guadalajara
instacron:UDG
instname_str Universidad de Guadalajara
instacron_str UDG
institution UDG
reponame_str Repositorio UDG CUALTOS
collection Repositorio UDG CUALTOS
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1858177468729393152
score 15,81155

Similares en LA Referencia