Lung lesions in opossums (Didelphis virginiana) naturally infected by Paragonimus mexicanus in Colima, Mexico

Paragonimiasis is a zoonotic disease in Mexico caused by adult digeneans of Paragonimus mexicanus species. Life cycle of this parasite involves two necessary intermediate hosts: a snail and a crab, and a mammal serving as the definitive host. Humans acquire the infection when eating raw or undercook...

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Detalles Bibliográficos
Autores: Luis Jorge García-Márquez, José Luis Vázquez-García, David Osorio-Sarabia, Virginia León-Régagnon, Luis García-Prieto, Rafael Lamothe-Argumedo, Fernando Constantino-Casas
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:México
Institución:Universidad Nacional Autónoma de México
Repositorio:Redalyc-UNAM
OAI Identifier:oai:redalyc.org:42312453006
Acceso en línea:https://www.redalyc.org/articulo.oa?id=42312453006
Access Level:acceso abierto
Palabra clave:Veterinaria
helmintos
tlacuaches
Paragonimiasis
histopatología
didelphis virginiana
Descripción
Sumario:Paragonimiasis is a zoonotic disease in Mexico caused by adult digeneans of Paragonimus mexicanus species. Life cycle of this parasite involves two necessary intermediate hosts: a snail and a crab, and a mammal serving as the definitive host. Humans acquire the infection when eating raw or undercooked crabs infected by metacercariae. In March 2005, six opossums (Didelphis virginiana) were captured in Colima, Mexico. These opossums were euthanized in order to identify lesions caused by lung paragonimiasis. Infected lungs were processed and stained following the standard histological techniques. Four of the six opossums (67%) carried 25 adult parasites identified as P. mexicanus. The lung with the greatest number of parasites showed 13 multifocally distributed granulomas. The main histological changes were: infiltration of monocytes, lymphocytes, macrophages, plasma cells, epithelioid and giant cells, abundant neutrophils and eosinophils, as well as central necrosis of the eosinophilic granuloma. Likewise, interstitial pneumonia was observed due to the presence of eggs between the granuloma walls and alveolar spaces. This study represents the first description of the pulmonary lesions caused by P. mexicanus in wild mammals.