Plasma gradient modified scaffolds to generate a chemoattractant surface

A gradient of plasma polymerization of pyrrole was generate d to model a chemoattractant surface; it was obtained by changing the polymerization tim e to manipulate the thickness and the deposite d layer. The polymerization was generated with a power of 30W on a cylindrical vac uum reactor, the cove...

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Detalles Bibliográficos
Autores: O. Ramírez-Fernández, R. Godínez, E. Zúñiga-Aguilar, C. A. López-Cobá, J. Morales, R. Olayo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:México
Institución:Universidad Autónoma Metropolitana
Repositorio:Redalyc-UAM
OAI Identifier:oai:redalyc.org:94231175005
Acceso en línea:https://www.redalyc.org/articulo.oa?id=94231175005
Access Level:acceso abierto
Palabra clave:Física, Astronomía y Matemáticas
Ito cells
Chemotaxis
Cell Culture
Biomaterials
Chemoattractant
Descripción
Sumario:A gradient of plasma polymerization of pyrrole was generate d to model a chemoattractant surface; it was obtained by changing the polymerization tim e to manipulate the thickness and the deposite d layer. The polymerization was generated with a power of 30W on a cylindrical vac uum reactor, the coverslip was polymerized covered by a cavity with a surface exposed of 0.7 cm every 35 min., the cells seeded were liver stellate cells (Ito); it was evaluated against a coverslip with continuous plasma polymerization of pyrrole (Ppy). The results show similar protein secret ions, but cells proliferation was selective in the surface gradient regions.