Differential effects of interleukin 6 immediately after acute social stress: preliminary results
Purpose: To evaluate the differential effect of acute social stress on IL-6 using the Trier Social Stress Test (TSST).Methodology: Seventeen normotensive university students whose mean arterial pressure was recorded in three moments, 10 min before, pre and post TSST participated. A sample of salivar...
| Autores: | , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2020 |
| País: | México |
| Institución: | UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO |
| Repositorio: | Entreciencias: diálogos en la sociedad del conocimiento |
| Idioma: | español |
| OAI Identifier: | oai:ojs.pkp.sfu.ca:article/70467 |
| Acceso en línea: | https://revistas.unam.mx/index.php/entreciencias/article/view/70467 |
| Access Level: | acceso abierto |
| Palabra clave: | TSST IL-6 Mean Arterial Pressure Stress. Presión Arterial Media Estrés. |
| Sumario: | Purpose: To evaluate the differential effect of acute social stress on IL-6 using the Trier Social Stress Test (TSST).Methodology: Seventeen normotensive university students whose mean arterial pressure was recorded in three moments, 10 min before, pre and post TSST participated. A sample of salivary IL-6 pre-post TSST was also collected. Results: There was an increase in mean arterial pressure only when the TSST was present (p<0.001). The level of IL-6 pre-post TSST showed no statistically significant changes (p> 0.05). However, a thorough analysis of the effects of TSST on IL-6 revealed that 53 % of the sample increased their concentration of IL-6 (p <0.001) while 47 % of the participants decreased their IL-6 level (p <0.01); there is a statistically significant difference between these two subgroups (p<0.05). Limitations: It is recommended to establish normative parameters of salivary IL-6.Findings: The preliminary data we present suggests that acute social stress increases blood pressure, but that this effect induces a differential expression of IL-6 in all participants. In participants with a low concentration of IL-6, it increases after acute stress, while for those with a previous high level of IL-6, the test tends to decrease it. |
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