Genotoxic risk in agricultural workers exposed to pesticides

Pesticides are chemical agents widely used by humans to protect the crops and livestock from nocive organisms as pests and vectors highly important in public health as well as in domestic applications. These substances has been considered potential mutagens because they contain ingredients capable t...

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Bibliographic Details
Authors: MARTÍNEZ-VALENZUELA, Carmen, GÓMEZ-ARROYO, Sandra
Format: article
Status:Published version
Publication Date:2010
Country:México
Institution:UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO
Repository:Revista Internacional de Contaminación Ambiental
Language:Spanish
OAI Identifier:oai:ojs.pkp.sfu.ca:article/21636
Online Access:https://www.revistascca.unam.mx/rica/index.php/rica/article/view/21636
Access Level:Open access
Keyword:plaguicidas
exposición ocupacional
riesgo genotóxico
biomonitoreo citogenético
aberraciones cromosómicas
micronúcleos
intercambio de cromátidas hermanas
ensayo cometa
Description
Summary:Pesticides are chemical agents widely used by humans to protect the crops and livestock from nocive organisms as pests and vectors highly important in public health as well as in domestic applications. These substances has been considered potential mutagens because they contain ingredients capable to cause changes in the deoxyribonucleic acid (DNA). As one of the most important problems is the occupational exposure to these compounds many studies have been made in order to evaluate the risk in its use, mainly of agriculture workers, through evaluation of chromosomal aberrations (CA), micronuclei (MN), sister chromatid exchanges (SCE) and comet assay (CA). The results have been contradictory, because there are several factors that influence them, as the active ingredients, technical formulations and chemical groups which they belong, the type of exposure (acute or chronic), type of contact (direct or indirect), the amount used, duration and intensity of the applications, the exposure to mixtures, climate and the seasons of the year when the application were made, the age of the persons, among other factors. Based in the mentioned above, series of studies in the last twenty years will be shown to evaluate the risk of the field workers.